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LY2940680

Known as: LY-2940680 
National Institutes of Health

Papers overview

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2018
2018
Purpose: The purpose of this study was to determine a recommended phase II dose and schedule of LY2940680 (taladegib) for safe… 
2016
2016
The Hedgehog (HH) pathway has been linked to the formation of basal cell carcinoma (BCC), medulloblastoma, and other cancers. The… 
Review
2015
Review
2015
The Hedgehog (Hh) signaling pathway is critical for embryonic development. In adult tissues, Hh signaling is relatively quiescent… 
2015
2015
We investigated the sensitivity of intrahepatic cholangiocarcinoma (IHCCA) subtypes to chemotherapeutics and molecular targeted… 
2015
2015
The Smoothened (Smo) receptor, a member of class F G protein‐coupled receptors, is the main transducer of the Hedgehog (Hh… 
Review
2014
Review
2014
Introduction: Basal cell carcinoma (BCC) is a malignancy that is driven by an activated Hedgehog (Hh) pathway. Smoothened… 
Highly Cited
2013
Highly Cited
2013
The smoothened (SMO) receptor, a key signal transducer in the hedgehog signalling pathway, is responsible for the maintenance of…