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LY2940680

Known as: LY-2940680 
 
National Institutes of Health

Papers overview

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2018
2018
Purpose: The purpose of this study was to determine a recommended phase II dose and schedule of LY2940680 (taladegib) for safe… Expand
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2016
2016
The Hedgehog (HH) pathway has been linked to the formation of basal cell carcinoma (BCC), medulloblastoma, and other cancers. The… Expand
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Review
2015
Review
2015
The Hedgehog (Hh) signaling pathway is critical for embryonic development. In adult tissues, Hh signaling is relatively quiescent… Expand
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2015
2015
We investigated the sensitivity of intrahepatic cholangiocarcinoma (IHCCA) subtypes to chemotherapeutics and molecular targeted… Expand
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2015
2015
The Smoothened (Smo) receptor, a member of class F G protein-coupled receptors, is the main transducer of the Hedgehog (Hh… Expand
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2014
2014
BACKGROUND The smoothened (SMO) receptor, one of the Class F G protein coupled receptors (GPCRs), is an essential component of… Expand
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Review
2014
Review
2014
INTRODUCTION Basal cell carcinoma (BCC) is a malignancy that is driven by an activated Hedgehog (Hh) pathway. Smoothened… Expand
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2014
2014
Nowadays, obesity becomes a serious global problem, which can induce a series of diseases such as type 2 diabetes mellitus… Expand
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Highly Cited
2013
Highly Cited
2013
The smoothened (SMO) receptor, a key signal transducer in the hedgehog signalling pathway, is responsible for the maintenance of… Expand
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