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LY-156758

Known as: LY 156758, LY156758 
National Institutes of Health

Papers overview

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Highly Cited
2002
Highly Cited
2002
Amino acid Asp-351 in the ligand binding domain of estrogen receptor α (ERα) plays an important role in regulating the estrogen… Expand
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Review
2000
Review
2000
  • A. Wakeling
  • Endocrine-related cancer
  • 2000
  • Corpus ID: 7172460
Since the description of the first antioestrogen, MER 25, more than four decades ago (Lerner et al. 1958), and of tamoxifen ten… Expand
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Highly Cited
1996
Highly Cited
1996
It is imperative to develop new agents for the prevention of breast cancer, considering the incidence of this disease and its… Expand
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Highly Cited
1996
Highly Cited
1996
Estrogen or raloxifene (LY156758) prevent estrogen deficiency-induced bone loss in animals and humans. We demonstrated in the rat… Expand
Highly Cited
1988
Highly Cited
1988
Fourteen patients with disseminated breast cancer with primary or secondary resistance to tamoxifen were treated with LY156758… Expand
Highly Cited
1986
Highly Cited
1986
We have examined the effect of androst-5-ene-3 beta,17 beta-diol (delta 5-diol) and its precursors, dehydroepiandrosterone (DHEA… Expand
Highly Cited
1986
Highly Cited
1986
Estradiol amplified synergistically the dose- and time-dependent stimulatory actions of human somatomedin-C on progesterone… Expand
Highly Cited
1985
Highly Cited
1985
Endocrine therapy with estrogen deprivation or with antiestrogens results in tumor regression in a subset of patients with… Expand
Highly Cited
1984
Highly Cited
1984
In an effort to prepare nonsteroidal antiestrogens demonstrating greater antagonism and less intrinsic estrogenicity than those… Expand
Highly Cited
1983
Highly Cited
1983
Keoxifene (LY156758) is a new benzothiophene-derived antiestrogen with an extremely low degree of estrogenicity. Administration… Expand