LNP 911

Known as: LNP-911, LNP911 
 
National Institutes of Health

Papers overview

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2018
2018
DNA-loaded nano-adjuvant formed with a vitamin E-scaffold intracellular environmentally-responsive lipid-like material for cancer immunotherapy.
Cytoplasmic DNA triggers cellular immunity via activating the stimulator of interferon genes pathway. Since DNA is degradable and… Expand
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2017
2017
Preclinical Pharmacology and Pharmacokinetics of Inhaled Hexadecyl-Treprostinil (C16TR), a Pulmonary Vasodilator Prodrug.
This article describes the preclinical pharmacology and pharmacokinetics (PK) of hexadecyl-treprostinil (C16TR), a prodrug of… Expand
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2015
2015
Proof-of-concept Studies for siRNA-mediated Gene Silencing for Coagulation Factors in Rat and Rabbit
The present study aimed at establishing feasibility of delivering short interfering RNA (siRNA) to target the coagulation cascade… Expand
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2014
2014
Exchange rate fluctuations, plant turnover and productivity
In a small open economy, fluctuations in the real exchange rate can affect plant turnover, and thus aggregate productivity, by… Expand
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2014
2014
Nonlinear Behaviors of Tail Dependence and Cross-Correlation of Financial Time Series Model
Nonlinear behaviors of tail dependence and cross-correlation of financial time series are reproduced and investigated by… Expand
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2012
2012
Intravesical delivery of small activating RNA formulated into lipid nanoparticles inhibits orthotopic bladder tumor growth.
Practical methods for enhancing protein production in vivo remain a challenge. RNA activation (RNAa) is emerging as one potential… Expand
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2011
2011
Activation of Latent HIV Using Drug-Loaded Nanoparticles
Antiretroviral therapy is currently only capable of controlling HIV replication rather than completely eradicating virus from… Expand
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2010
2010
Tumor targeting of functionalized lipid nanoparticles: assessment by in vivo fluorescence imaging.
Lipid nanoparticles (LNP) coated by a poly(oxyethylene) polymer have been manufactured from low cost and human use-approved… Expand
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Review
2003
Review
2003
I(1) imidazoline receptors involved in cardiovascular regulation: where are we and where are we going?
Clonidine-like drugs (hybrid drugs) reduce blood pressure by acting centrally at both alpha(2)-adrenergic receptors (alpha(2)AR… Expand
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1998
1998
Discrete-event simulation on the bulk-synchronous parallel model
The bulk-synchronous parallel (BSP) model of computing has been proposed to enable the development of portable software which… Expand
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