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LNP 911

Known as: LNP-911, LNP911 
 
National Institutes of Health

Papers overview

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2019
2019
Lipid‐nucleic acid nanoparticles of novel ionizable lipids for systemic BMP‐9 gene delivery to bone‐marrow mesenchymal stem cells for osteoinduction
Graphical abstract Figure. No caption available. ABSTRACT Rational design of novel ionizable lipids for development of lipid… Expand
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2018
2018
Effective Therapy Using a Liposomal siRNA that Targets the Tumor Vasculature in a Model Murine Breast Cancer with Lung Metastasis
Although metastatic cancer is a major cause of death for cancer patients, no efficacious treatment for metastasis is available… Expand
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2017
2017
Design of lipid nanoparticles for in vitro and in vivo delivery of plasmid DNA.
Lipid nanoparticles (LNPs) containing distearoylphosphatidlycholine (DSPC), and ionizable amino-lipids such as dilinoleylmethyl-4… Expand
2017
2017
Rapid synthesis of lipid nanoparticles containing hydrophobic inorganic nanoparticles.
A straightforward "bottom-up" synthesis is described for efficient entrapment of inorganic hydrophobic nanoparticles (HNPs… Expand
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2015
2015
Systemic delivery of axitinib with nanohybrid liposomal nanoparticles inhibits hypoxic tumor growth.
Axitinib (AXT) is a potent and selective orally administered inhibitor of the vascular endothelial growth factor receptors 1-3… Expand
2015
2015
Proof-of-concept Studies for siRNA-mediated Gene Silencing for Coagulation Factors in Rat and Rabbit
The present study aimed at establishing feasibility of delivering short interfering RNA (siRNA) to target the coagulation cascade… Expand
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2014
2014
Exchange Rate Fluctuations, Plant Turnover and Productivity
In a small open economy, fluctuations in the real exchange rate can affect plant turnover, and thus aggregate productivity, by… Expand
Highly Cited
2012
Highly Cited
2012
Intravesical delivery of small activating RNA formulated into lipid nanoparticles inhibits orthotopic bladder tumor growth.
Practical methods for enhancing protein production in vivo remain a challenge. RNA activation (RNAa) is emerging as one potential… Expand
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Highly Cited
2011
Highly Cited
2011
Activation of Latent HIV Using Drug-Loaded Nanoparticles
Antiretroviral therapy is currently only capable of controlling HIV replication rather than completely eradicating virus from… Expand
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Highly Cited
2010
Highly Cited
2010
Tumor targeting of functionalized lipid nanoparticles: assessment by in vivo fluorescence imaging.
Lipid nanoparticles (LNP) coated by a poly(oxyethylene) polymer have been manufactured from low cost and human use-approved… Expand
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