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LMB-1 immunotoxin

Known as: B3-NLysPE38, Immunotoxin LMB-1, LMB-1 
A chimeric protein consisting of the Fv portion of a monoclonal antibody attached to a fragment of Pseudomonas exotoxin A without its cell-binding… Expand
National Institutes of Health

Papers overview

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2019
2019
The number of cases of infection with carbapenem-resistant Enterobacteriaceae (CRE) has been increasing and has become a major… Expand
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2018
2018
Objectives To identify and characterize a novel MBL gene conferring carbapenem resistance to an isolate of Enterobacter cloacae… Expand
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2017
2017
Protocatechuate 3,4-dioxygenase (P34O), which is isolated from Rhizobium sp. LMB-1, catalyzes the ring cleavage step in the… Expand
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2017
2017
DNA isolated from a greenhouse soil (Nanjing, Jiangsu Province, China) was suitable for PCR amplification of gene segment coding… Expand
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2016
2016
To isolate a novel strain that could degrade many kinds PAEs efficiently and investigate the DBP‐degrading pathway in this strain… Expand
2004
2004
Purpose: Rituximab, a humanized monoclonal antibody directed to the CD20 antigen present on B lymphocytes, could potentially… Expand
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1997
1997
PE38 is a 38‐kDa derivative of the 66‐kDa Pseudomonas exotoxin (PE) in which the cell binding domain of PE (domain Ia, amino… Expand
Highly Cited
1995
Highly Cited
1995
Vascular leak syndrome (VLS) was originally found to be a major dose-limiting toxicity in humans with cancer treated with several… Expand
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1995
1995
LMB-1 (B3-LysPE38) is an immunotoxin composed of the tumor-reactive monoclonal antibody B3 and a genetically engineered form of… Expand
1994
1994
NLysPE38 is a 38-kDa derivative of Pseudomonas exotoxin (PE) in which domain Ia (amino acids 1 to 252) and part of domain Ib (365… Expand