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LMB-1 immunotoxin

Known as: B3-NLysPE38, Immunotoxin LMB-1, LMB-1 
A chimeric protein consisting of the Fv portion of a monoclonal antibody attached to a fragment of Pseudomonas exotoxin A without its cell-binding… 
National Institutes of Health

Related topics

Related topics

5 relations
ApoptosisPeptide Elongation Factor 2Translational Repressionmitochondrial toxicity

Broader (1)

Immunotoxins

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Identification of the di-n-butyl phthalate-biodegrading strains and the biodegradation pathway in strain LMB-1
DNA isolated from a greenhouse soil (Nanjing, Jiangsu Province, China) was suitable for PCR amplification of gene segment coding… 
2007
2007
APhase I Biodistribution and PharmacokineticTrial of Humanized Monoclonal Antibody Hu3s193 in Patients with Advanced Epithelial Cancers that Express the Lewis-YAntigen
Purpose:We report a first-in-man trial of a humanized antibody (hu3S193) against the Le antigen. Experimental Design: Patients… 
1997
1997
Identification of epitopes on a mutant form of Pseudomonas exotoxin using serum from humans treated with Pseudomonas exotoxin containing immunotoxins
PE38 is a 38‐kDa derivative of the 66‐kDa Pseudomonas exotoxin (PE) in which the cell binding domain of PE (domain Ia, amino… 
1995
1995
Efficacy of compartmental administration of immunotoxin LMB-1 (B3-LysPE38) in a rat model of carcinomatous meningitis.
LMB-1 (B3-LysPE38) is an immunotoxin composed of the tumor-reactive monoclonal antibody B3 and a genetically engineered form of… 
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