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LIM and SH3 Domain Protein 1

Known as: MLN 50, Metastatic Lymph Node Gene 50 Protein, LASP1 
LIM and SH3 domain protein 1 (261 aa, ~30 kDa) is encoded by the human LASP1 gene. This protein is involved in the regulation of actin-associated… 
National Institutes of Health

Related topics

Related topics

11 relations
Actin-Binding ProteinCellular MembraneCytoskeletonIntracellular Transport

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
[Study on the effects of microRNA-203 on the invasion and apoptosis of laryngeal cancer cells via targeting LASP1].
Objective: To explore the role of microRNA-203 in laryngeal cancer and its underlying mechanism and clarify the relationship… 
2018
2018
MicroRNA-203 inhibits invasion and induces apoptosis of laryngeal cancer cells via targeting LASP1.
OBJECTIVE To explore the role of microRNA-203 in laryngeal cancer and its underlying mechanism in regulating cell invasion and… 
2017
2017
Role of LASP-1, a novel SOX9 transcriptional target, in the progression of lung cancer.
Lung cancer accounts for most cancer-related deaths worldwide. However, the underlying mechanism by which it mediates the… 
2016
2016
A10.15 LASP-1 modifies ECM-synovial fibroblast interactions in a mouse model of ra
Background and objectives The LIM-and-SH3-domain-protein-1 (Lasp-1) is an actin-associated protein and is localised at focal… 
2015
2015
A2.11 LASP-1 deficiency is changing synovial fibroblast interaction with cartilage matrix in TNFα mediated arthritis
Background and objectives Lasp-1 (LIM-and-SH3-domain-protein-1) is an actin-binding protein that modifies cytoskeleton… 
2014
2014
A1.23 Lasp-1 deficiency modifies synovial fibroblast migration and cartilage destruction in a model of HTNF alpha mediated arthritis
Background and Objectives Lasp-1 is an important actin-crosslinking protein. It’s localises at focal adhesions, along stress… 
2013
2013
A8.15 The Focal Contact Protein Lasp-1 Modulates the Migration Capacity of Synovial Fibroblasts
Background and Objectives RA synovial fibroblasts (SF) have been suggested to contribute to the spreading of disease through… 
2011
2011
506 FUNCTIONAL ROLE OF LASP1 IN BLADDER CANCER CELL VIABILITY AND ITS REGULATION BY MICRORNAS
2009
2009
Lasp1 misexpression influences chondrocyte differentiation in the vertebral column.
The mouse mutant wavy tail Tg(Col1a1-lacZ)304ng was created through transgene insertion and exhibits defects of the vertebral… 
1998
1998
Lasp-1 is a regulated phosphoprotein within the cAMP signaling pathway in the gastric parietal cell.
Activation of the cAMP signaling pathway is correlated with increased secretory-related events in a wide variety of cell types… 
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