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LIG3 gene

Known as: LIG3, LIGASE III, DNA, ATP-DEPENDENT, Ligase III, DNA, ATP-Dependent Gene 
This gene is involved in DNA double-strand break repair.
National Institutes of Health

Related topics

Related topics

4 relations
Base Excision RepairDNA ligase IIILIG3 protein, humanMitotic Recombination

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
Association between Single-Nucleotide Polymorphisms of the hOGG1,NEIL1,APEX1, FEN1,LIG1, and LIG3 Genes and Alzheimer's Disease Risk
Background: One of the factors that contribute to Alzheimer's disease (AD) is the DNA damage caused by oxidative stress and… 
2016
2016
A computational approach to determine susceptibility to cancer by evaluating the deleterious effect of nsSNP in XRCC1 gene on binding interaction of XRCC1 protein with ligase III.
2015
2015
Efficiency of Base Excision Repair of Oxidative DNA Damage and Its Impact on the Risk of Colorectal Cancer in the Polish Population
DNA oxidative lesions are widely considered as a potential risk factor for colorectal cancer development. The aim of this work… 
2015
2015
Alternative end joining, clonal evolution, and escape from a telomere-driven crisis
Telomere dysfunction and fusion play key roles in driving genomic instability and clonal evolution in many tumor types. We have… 
2011
2011
Disconnecting XRCC1 and DNA ligase III
DNA strand break repair is essential for the prevention of multiple human diseases, particularly those which feature… 
2011
2011
Association between single nucleotide polymorphisms in the DNA repair gene LIG3 and acute adverse skin reactions following radiotherapy.
2009
2009
Multiplex RT-PCR Expression Analysis of Developmentally Important Genes in Individual Mouse Preimplantation Embryos and Blastomeres1
Abstract We have developed a microfluidic chip-based qualitative assay for sensitive (10 RNA copies) detection of multiple… 
Highly Cited
2007
Highly Cited
2007
Low levels of DNA ligases III and IV sufficient for effective NHEJ
Cells of higher eukaryotes rejoin double strand breaks (DSBs) in their DNA predominantly by a non‐homologous DNA end joining… 
2003
2003
Evaluation of a microarray for genotyping polymorphisms related to xenobiotic metabolism and DNA repair.
We present an oligonucleotide microarray ("MetaboChip") based on the arrayed primer extension (APEX) technique, allowing… 
Review
1997
Review
1997
Mammalian DNA ligases
DNA joining enzymes play an essential role in the maintenance of genomic integrity and stability. Three mammalian genes encoding… 
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