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LGALS9 protein, human

Known as: Galectin 9, Urate Transporter/Channel Protein, Tumor Antigen HOM-HD-21 
Galectin-9 (355 aa, ~40 kDa) is encoded by the human LGALS9 gene. This protein plays a role in galactoside binding and as an eosinophil… Expand
National Institutes of Health

Papers overview

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Review
2018
Review
2018
Galectins are glycan-binding proteins that contain one or two carbohydrate domains and mediate multiple biological functions. By… Expand
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Highly Cited
2012
Highly Cited
2012
The S-type lectin galectin-9 binds to the negative regulatory molecule Tim-3 on T cells and induces their apoptotic deletion or… Expand
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Review
2011
Review
2011
T cell immunoglobulin-3 (Tim-3) has been identified as a marker of differentiated interferon-γ-producing CD4(+) T helper type 1… Expand
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Highly Cited
2010
Highly Cited
2010
IFN-γ plays a central role in antitumor immunity. T cell Ig and mucin domain (Tim-3) is expressed on IFN-γ–producing Th1 cells… Expand
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Highly Cited
2010
Highly Cited
2010
In this communication, we demonstrate that galectin (Gal)-9 acts to constrain CD8+ T cell immunity to Herpes Simplex Virus (HSV… Expand
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Highly Cited
2009
Highly Cited
2009
Epstein-Barr virus (EBV)-associated nasopharyngeal carcinoma (NPC) is the third most frequent virus-associated human malignancy… Expand
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Highly Cited
2008
Highly Cited
2008
A Tim-3 ligand, galectin-9 (Gal-9), modulates various functions of innate and adaptive immune responses. In this study, we… Expand
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Highly Cited
2007
Highly Cited
2007
The T cell immunoglobulin mucin (Tim) family of receptors regulates effector CD4(+) T cell functions and is implicated in… Expand
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Highly Cited
2005
Highly Cited
2005
Tim-3 is a T helper type 1 (TH1)–specific cell surface molecule that seems to regulate TH1 responses and the induction of… Expand
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Highly Cited
2001
Highly Cited
2001
Purpose: Knowledge about galectin expression by human tumor cells is mainly restricted to galectins-1 and -3. This study was… Expand
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