LEBER CONGENITAL AMAUROSIS, TYPE II (disorder)

Known as: Amaurosis congenita of Leber, type 2, Leber congenital amaurosis type 2, Leber Congenital Amaurosis 2 
 
National Institutes of Health

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Topic mentions per year

1988-2016
012319882016

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2015
2015
Spark Therapeutics recently reported positive phase III results for SPK-RPE65 targeting the treatment of visual impairment caused… (More)
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2013
Highly Cited
2013
OBJECTIVE The aim of this study was to show the clinical data of long-term (3-year) follow-up of 5 patients affected by Leber… (More)
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2013
2013
About 5 years ago, results were made public from three independent early phase clinical gene therapy trials for an inherited and… (More)
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2012
2012
Leber congenital amaurosis (LCA) is one of the most severe forms of inherited retinal degeneration and can be caused by mutations… (More)
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2011
2011
Leber congenital amaurosis (LCA) is a rare degenerative eye disease, linked to mutations in at least 14 genes. A recent gene… (More)
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2011
2011
RPE65 is an abundantly expressed protein within the retinal pigment epithelium (RPE) of the eye that is required for retinoid… (More)
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2010
Highly Cited
2010
The safety and efficacy of gene therapy for inherited retinal diseases is being tested in humans affected with Leber's congenital… (More)
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2008
Highly Cited
2008
Leber's congenital amaurosis (LCA) is a group of inherited blinding diseases with onset during childhood. One form of the disease… (More)
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2002
2002
BACKGROUND Leber's congenital amaurosis (LCA) encompasses the most precocious and severe forms of inherited retinal dystrophy… (More)
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1997
Highly Cited
1997
Autosomal recessive childhood-onset severe retinal dystrophy (arCSRD) designates a heterogeneous group of disorders affecting rod… (More)
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