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LDL-Receptor Related Protein 2
Known as:
LRP 2 Receptor
, Renal Glycoprotein GP330
, LDL Receptor Related Protein 2
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An LDL-RECEPTOR RELATED PROTEIN found in the neuroepithelium and in proximal tubular cells of the kidney. It is considered a multiligand receptor in…
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National Institutes of Health
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Related topics
Related topics
9 relations
Broader (1)
Heymann Nephritis Antigenic Complex
In Blood
LRP2 gene
Low Density Lipoprotein Receptor
agonists
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Narrower (1)
low-density lipoprotein receptor-related protein 2, human
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Maternofetal transport of vitamin B12: role of TCblR/CD320 and megalin
Kaveri Arora
,
J. M. Sequeira
,
E. Quadros
The FASEB Journal
2017
Corpus ID: 23278505
Vitamin B12 deficiency causes megaloblastic anemia and neurologic disorder in humans. Gene defects of transcobalamin (TC) and the…
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2016
2016
Retinoid Homeostatic Gene Expression in Liver, Lung and Kidney: Ontogeny and Response to Vitamin A-Retinoic Acid (VARA) Supplementation from Birth to Adult Age
S. Owusu
,
A. Ross
PLoS ONE
2016
Corpus ID: 16561520
Vitamin A (VA, retinol) metabolism is homeostatically controlled, but little is known of its regulation in the postnatal period…
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2010
2010
Nephrotoxicity in Mice After Repeated Imaging Using 111In-Labeled Peptides
M. Melis
,
E. Vegt
,
+6 authors
M. de Jong
Journal of Nuclear Medicine
2010
Corpus ID: 13239225
We determined the renal radiation dose of a series of 111In-labeled peptides using animal SPECT. Because the animals' health…
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2007
2007
Absence of ClC5 in Knockout Mice Leads to Glycosuria, Impaired Renal Glucose Handling and Low Proximal Tubule GLUT2 Protein Expression
J. Souza-Menezes
,
M. Morales
,
D. Tukaye
,
S. Guggino
,
W. Guggino
Cellular Physiology and Biochemistry
2007
Corpus ID: 34369655
Glycosuria is one of the well-documented characteristics in ClC-5 knockout (KO) mice and patients with Dent’s disease. However…
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Review
2005
Review
2005
Role of megalin, a proximal tubular endocytic receptor, in the pathogenesis of diabetic and metabolic syndrome‐related nephropathies: protein metabolic overload hypothesis
A. Saito
,
T. Takeda
,
+10 authors
F. Gejyo
Nephrology
2005
Corpus ID: 42737684
SUMMARY: Megalin is an endocytic receptor on the apical membranes of proximal tubule cells (PTC) in the kidney, and is involved…
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2003
2003
Mechanisms for the reduction of 24,25‐dihydroxyvitamin D3 levels and bone mass in 24‐hydroxylase transgenic rats
N. Hosogane
,
T. Shinki
,
H. Kasuga
,
S. Taketomi
,
Y. Toyama
,
T. Suda
The FASEB Journal
2003
Corpus ID: 31692244
24‐Hydroxylase (CYP24) is an enzyme distributed in the target tissues of 1α,25‐dihydroxyvitamin D3 [1α,25(OH)2D3]. Two functions…
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2002
2002
Effect of gentamicin on pharmacokinetics of lysozyme in rats: interaction between megalin substrates in the kidney
J. Nagai
,
T. Katsube
,
T. Murakami
,
M. Takano
The Journal of pharmacy and pharmacology
2002
Corpus ID: 33269634
To investigate the pharmacokinetic interaction between substrates of megalin, a 600‐kDa endocytic receptor abundantly expressed…
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1999
1999
Cell- and region-specific localization of lysosomal and secretory proteins and endocytic receptors in epithelial cells of the cauda epididymidis and vas deferens of the adult rat.
S. Andonian
,
L. Hermo
Journal of Andrology
1999
Corpus ID: 7893918
The epithelial cells lining the cauda epididymidis and vas deferens are active in endocytosis and have an abundance of lysosomes…
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Review
1998
Review
1998
Molecular Interactions between Albumin and Proximal Tubular Cells
N. Brunskill
Nephron Experimental Nephrology
1998
Corpus ID: 29044944
In glomerular diseases the filtration of excess proteins into the proximal tubule, together with their subsequent reabsorption…
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Review
1997
Review
1997
Cell biology of aminoglycoside nephrotoxicity: newer aspects
B. Molitoris
Current opinion in nephrology and hypertension
1997
Corpus ID: 6856426
&NA; Recent advances in the understanding of the cell biology of aminoglycoside antibiotics have answered some questions and…
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