LATS2 gene

Known as: LATS2, LARGE TUMOR SUPPRESSOR, DROSOPHILA, HOMOLOG OF, 2, large tumor suppressor kinase 2 
This gene plays a role in the maintenance of genomic stability.
National Institutes of Health

Papers overview

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Highly Cited
2012
Highly Cited
2012
Here we report that miR-93, a miRNA in the miR-106B~25 cluster, a paralog of the miR-17-92 cluster, was significantly upregulated… (More)
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2012
2012
Snail1 is a central regulator of epithelial cell adhesion and movement in epithelial-to-mesenchymal transitions (EMTs) during… (More)
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Highly Cited
2012
Highly Cited
2012
High-grade osteosarcoma is a tumor with a complex genomic profile, occurring primarily in adolescents with a second peak at… (More)
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Highly Cited
2011
Highly Cited
2011
Malignant mesothelioma (MM) is an aggressive neoplasm associated with asbestos exposure. We carried out genome-wide array-based… (More)
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Highly Cited
2007
Highly Cited
2007
Tumor suppressor Lats2 is a member of the conserved Dbf2 kinase family. It localizes to the centrosome and has been implicated in… (More)
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Highly Cited
2006
Highly Cited
2006
Damage to the mitotic spindle and centrosome dysfunction can lead to cancer. To prevent this, cells trigger a succession of… (More)
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Highly Cited
2006
Highly Cited
2006
Endogenous small RNAs (miRNAs) regulate gene expression by mechanisms conserved across metazoans. While the number of verified… (More)
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Highly Cited
2006
Highly Cited
2006
LATS1 and LATS2 are tumor suppressor genes implicated in the regulation of cell cycle, but their methylation statuses are still… (More)
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Highly Cited
2004
Highly Cited
2004
Human Lats2, a novel serine/threonine kinase, is a member of the Lats kinase family that includes the Drosophila tumour… (More)
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Highly Cited
2003
Highly Cited
2003
Lats2 is a new member of the Lats tumor suppressor family. The human LATS2 gene is located at chromosome 13q11–12, which has been… (More)
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