LAG3 gene

Known as: LAG3, CD223, lymphocyte activating 3 
This gene is involved in the activation of T-cells and natural killer cells.
National Institutes of Health

Papers overview

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Review
2017
Review
2017
The treatment of bladder cancer has evolved over time to encompass not only the traditional modalities of chemotherapy and… (More)
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Review
2017
Review
2017
Despite the impressive impact of CTLA4 and PD1-PDL1-targeted cancer immunotherapy, a large proportion of patients with many tumor… (More)
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Review
2016
Review
2016
The immune system maintains a critically organized network to defend against foreign particles, while evading self-reactivity… (More)
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Highly Cited
2016
Highly Cited
2016
Emerging evidence indicates that the pathogenesis of Parkinson’s disease (PD) may be due to cell-to-cell transmission of… (More)
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Highly Cited
2013
Highly Cited
2013
Under conditions of chronic antigen stimulation, such as persistent viral infection and cancer, CD8 T cells may diminish effector… (More)
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Highly Cited
2009
Highly Cited
2009
Regulatory T cells (Tregs) are engaged in the maintenance of immunological self-tolerance and immune homeostasis. IL-10 has an… (More)
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Highly Cited
2005
Highly Cited
2005
Multiple sclerosis (MS) is a T-cell-mediated disease of the central nervous system, characterized by damage to myelin and axons… (More)
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Highly Cited
2005
Highly Cited
2005
Lymphocyte homeostasis is a central biological process that is tightly regulated. However, its molecular and cellular control is… (More)
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Highly Cited
1996
Highly Cited
1996
The LAG3 protein has several features in common with CD4, suggesting that it may be important in controlling T cell reactivity… (More)
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Highly Cited
1990
Highly Cited
1990
We have identified a novel human gene of the Ig superfamily, designated LAG-3. Expression of this gene is undetectable in resting… (More)
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