FAQ

L1CAM wt Allele

Known as: N-CAM-L1, MASA, L1-CAM 
Human L1CAM wild-type allele is located in the vicinity of Xq28 and is approximately 48 kb in length. This allele, which encodes neural cell adhesion… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1973-2018
051019732018

Related topics

Related topics

6 relations
Axon GuidanceCell AdhesionLigand BindingMigration, Cell
(More)

Related mentions per year

Related mentions per year

1936-2018
19401960198020002020
L1CAM wt Allele
Cell Adhesion
Migration, Cell
Neurogenesis
Axon Guidance
Xq28

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2011
2011
L1CAM regulates DNA damage checkpoint response of glioblastoma stem cells through NBS1.
Glioblastomas (GBMs) are highly lethal brain tumours with current therapies limited to palliation due to therapeutic resistance… (More)
  • figure 2
  • figure 3
  • figure 4
  • figure 5
  • figure 6
Is this relevant?
2009
2009
Nuclear translocation and signalling of L1-CAM in human carcinoma cells requires ADAM10 and presenilin/γ-secretase activity
L1-CAM (L1 cell-adhesion molecule), or more simply L1, plays an important role in the progression of human carcinoma… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
2009
2009
Enriched Environment Experience Overcomes Learning Deficits and Depressive-Like Behavior Induced by Juvenile Stress
Mood disorders affect the lives and functioning of millions each year. Epidemiological studies indicate that childhood trauma is… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
2008
2008
Shootin1 interacts with actin retrograde flow and L1-CAM to promote axon outgrowth
Actin polymerizes near the leading edge of nerve growth cones, and actin filaments show retrograde movement in filopodia and… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
2007
Highly Cited
2007
Expression of L1-CAM and ADAM10 in human colon cancer cells induces metastasis.
L1-CAM, a neuronal cell adhesion receptor, is also expressed in a variety of cancer cells. Recent studies identified L1-CAM as a… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
2007
2007
L1-CAM in a membrane-bound or soluble form augments protection from apoptosis in ovarian carcinoma cells.
OBJECTIVE Apoptosis resistance is a hallmark of cancer progression, a phenomenon frequently observed in ovarian carcinoma. We… (More)
Is this relevant?
2006
2006
A Conserved Role for Drosophila Neuroglian and Human L1-CAM in Central-Synapse Formation
BACKGROUND Drosophila Neuroglian (Nrg) and its vertebrate homolog L1-CAM are cell-adhesion molecules (CAM) that have been well… (More)
  • figure 1
  • table 1
  • figure 2
  • figure 3
  • table 2
Is this relevant?
2005
2005
Maintenance of neuronal positions in organized ganglia by SAX-7, a Caenorhabditis elegans homologue of L1.
The L1 family of cell adhesion molecules is predominantly expressed in the nervous system. Mutations in human L1 cause neuronal… (More)
  • figure 1
  • table I
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
2003
2003
L1-dependent neuritogenesis involves ankyrinB that mediates L1-CAM coupling with retrograde actin flow
The cell adhesion molecule L1 (L1-CAM) plays critical roles in neurite growth. Its cytoplasmic domain (L1CD) binds to ankyrins… (More)
Is this relevant?
1998
1998
Cis-activation of L1-mediated ankyrin recruitment by TAG-1 homophilic cell adhesion.
Neural cell adhesion molecules (CAMs) of the immunoglobulin (Ig) superfamily mediate not only cell aggregation but also growth… (More)
Is this relevant?