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L-iduronidase activity

Known as: alpha-L-iduronidase activity, glycosaminoglycan alpha-L-iduronohydrolase activity 
Catalysis of the hydrolysis of alpha-L-iduronosidic linkages in dermatan sulfate. [EC:3.2.1.76]
National Institutes of Health

Papers overview

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2018
2018
A Humoral Immune Response Alters the Distribution of Enzyme Replacement Therapy in Murine Mucopolysaccharidosis Type I
Antibodies against recombinant proteins can significantly reduce their effectiveness in unanticipated ways. We evaluated the… Expand
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Review
2015
Review
2015
Chitotriosidase and lysosomal enzymes as potential biomarkers of disease progression in amyotrophic lateral sclerosis: A survey clinic-based study
The aim of this study was to determine if blood chitotriosidase (Chit) activity and lysosomal enzyme levels might represent… Expand
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2010
2010
Characterization of an MPS I-H knock-in mouse that carries a nonsense mutation analogous to the human IDUA-W402X mutation.
Here we report the characterization of a knock-in mouse model for the autosomal recessive disorder mucopolysaccharidosis type I… Expand
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2005
2005
Prediction of neuropathology in mucopolysaccharidosis I patients.
Mucopolysaccharidosis I is a lysosomal storage disorder caused by a deficiency of the lysosomal hydrolase alpha-l-iduronidase… Expand
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