FAQ

L-cysteine desulfurase complex

Known as: IscS, L-cysteine desulfurase complex location, NifS 
A protein complex capable of cysteine desulfurase activity decomposing L-cysteine to L-alanine and sulfur. It belongs to a ubiquitous family of… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1973-2018
0102019732018

Related topics

Related topics

3 relations

Broader (1)

Cytoplasmic matrix

Narrower (1)

SufS complex
cysteine desulfurase activity

Related mentions per year

Related mentions per year

1947-2018
19401960198020002020
L-cysteine desulfurase complex
Cytoplasmic matrix
cysteine desulfurase activity
SufS complex

Papers overview

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Highly Cited
2016
Highly Cited
2016
Designer matrices for intestinal stem cell and organoid culture
Epithelial organoids recapitulate multiple aspects of real organs, making them promising models of organ development, function… (More)
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Highly Cited
2006
Highly Cited
2006
Role of human mitochondrial Nfs1 in cytosolic iron-sulfur protein biogenesis and iron regulation.
The biogenesis of iron-sulfur (Fe/S) proteins in eukaryotes is a complex process involving more than 20 components. So far… (More)
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Highly Cited
2003
Highly Cited
2003
An interaction between frataxin and Isu1/Nfs1 that is crucial for Fe/S cluster synthesis on Isu1.
Depletion of the mitochondrial matrix protein frataxin is the molecular cause of the neurodegenerative disease Friedreich ataxia… (More)
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Highly Cited
2003
Highly Cited
2003
Iron-sulfur cluster biosynthesis. Characterization of frataxin as an iron donor for assembly of [2Fe-2S] clusters in ISU-type proteins.
ISU (eukaryotes) and IscU (prokaryotes) are a homologous family of proteins that appear to provide a platform for assembly of… (More)
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Highly Cited
2002
Highly Cited
2002
Role of parity and human papillomavirus in cervical cancer: the IARC multicentric case-control study.
BACKGROUND High parity has long been suspected of being associated with an increased risk of cervical cancer, but previous… (More)
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Highly Cited
2001
Highly Cited
2001
ABA3 is a molybdenum cofactor sulfurase required for activation of aldehyde oxidase and xanthine dehydrogenase in Arabidopsis thaliana.
The xanthine oxidase class of molybdenum enzyzmes requires a terminal sulfur ligand at the active site. It has been proposed that… (More)
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Highly Cited
2000
Highly Cited
2000
The cysteine desulfurase, IscS, has a major role in in vivo Fe-S cluster formation in Escherichia coli.
The cysteine desulfurase, IscS, provides sulfur for Fe-S cluster synthesis in vitro, but a role for IscS in in vivo Fe-S cluster… (More)
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Highly Cited
1998
Highly Cited
1998
Assembly of iron-sulfur clusters. Identification of an iscSUA-hscBA-fdx gene cluster from Azotobacter vinelandii.
An enzyme having the same L-cysteine desulfurization activity previously described for the NifS protein was purified from a… (More)
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Highly Cited
1993
Highly Cited
1993
Cysteine desulfurase activity indicates a role for NIFS in metallocluster biosynthesis.
Biological nitrogen fixation is catalyzed by nitrogenase, a complex metalloenzyme composed of two separately purifiable component… (More)
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Highly Cited
1989
Highly Cited
1989
Biochemical and genetic analysis of the nifUSVWZM cluster from Azotobacter vinelandii
Azotobacter vinelandii genes contained within the major nif-cluster and designated orf6, nifU, nifS, nifV, orf7, orf8, nifW nifZ… (More)
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