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L 822429

Known as: L-822429, L822429 
 
National Institutes of Health

Papers overview

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2018
2018
BackgroundSeveral psychiatric conditions are affected by neuroinflammation and neuroimmune activation. The transcription factor… Expand
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2015
2015
Substance P (SP) and its cognate neurokinin-1 receptor (NK1R) are involved in alcohol-related behaviors. We have previously… Expand
2015
2015
Substance P and its preferred neurokinin receptor NK1 have been implicated in stress and anxiety and have been proposed as… Expand
2014
2014
Neurokinin-1 receptors (NK1Rs) have been shown to mediate alcohol and opiate, but not cocaine reward in rodents. We recently… Expand
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2014
2014
RationaleOperant self-administration (SA) is an important model of motivation to consume ethanol (EtOH), but low rates of… Expand
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2013
2013
Genetic deletion of the neurokinin 1 receptor (NK1R) has been shown to decrease the reinforcing properties of opioids, but it is… Expand
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2013
2013
BACKGROUND Genetic deletion or antagonism of the neurokinin 1 receptor (NK1R) decreases alcohol intake, alcohol reward, and… Expand
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Highly Cited
2011
Highly Cited
2011
RationaleGenetic inactivation or pharmacological antagonism of neurokinin 1 (NK1) receptors blocks morphine and alcohol reward in… Expand
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2011
2011
Increasing evidence suggests that specific physiological measures may serve as biomarkers for successful treatment to alleviate… Expand
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Highly Cited
2008
Highly Cited
2008
It has been shown that anxiety and stress responses are modulated by substance P (SP) released within the amygdala. However… Expand