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L 822429

Known as: L-822429, L822429 
National Institutes of Health

Papers overview

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2020
2020
Alcohol dependence induces hypersensitivity of the SP/NK-1R system and its regulation of CeA inhibitory transmission. Behavioral… 
2015
2015
Substance P and its preferred neurokinin receptor NK1 have been implicated in stress and anxiety and have been proposed as… 
2014
2014
Neurokinin-1 receptors (NK1Rs) have been shown to mediate alcohol and opiate, but not cocaine reward in rodents. We recently… 
2013
2013
Genetic deletion of the neurokinin 1 receptor (NK1R) has been shown to decrease the reinforcing properties of opioids, but it is… 
Highly Cited
2011
Highly Cited
2011
RationaleGenetic inactivation or pharmacological antagonism of neurokinin 1 (NK1) receptors blocks morphine and alcohol reward in… 
2011
2011
Increasing evidence suggests that specific physiological measures may serve as biomarkers for successful treatment to alleviate… 
Highly Cited
2008
Highly Cited
2008
It has been shown that anxiety and stress responses are modulated by substance P (SP) released within the amygdala. However…