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L 817818

Known as: L-817,818, L-817818, L817818 
 
National Institutes of Health

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2 relations

Broader (2)

AmidesNaphthalenes

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
Somatostatin regulates NHE8 protein expression via the ERK1/2 MAPK pathway in DSS-induced colitis mice.
Previous studies reported that administration of somatostatin (SST) to human patients mitigated their diarrheal symptoms… Expand
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2013
2013
Phosphorylation of threonine 333 regulates trafficking of the human sst5 somatostatin receptor.
The frequent overexpression of the somatostatin receptors sst2 and sst5 in neuroendocrine tumors provides the molecular basis for… Expand
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2010
2010
Activation of somatostatin receptor (sst5) protects the rat retina from AMPA-induced neurotoxicity
In a recent study, we employed an in vivo model of retinal excitotoxicity to investigate the neuroprotective effect of… Expand
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Highly Cited
2006
Highly Cited
2006
Internalization of sst2, sst3, and sst5 receptors: effects of somatostatin agonists and antagonists.
UNLABELLED The uptake of radiolabeled somatostatin analogs by tumor cells through receptor-mediated internalization is a critical… Expand
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2005
2005
Somatostatin increases voltage-gated K+ currents in GH3 cells through activation of multiple somatostatin receptors.
The secretion of GH by somatotropes is inhibited by somatostatin (SRIF) through five specific membrane receptors (SSTRs). SRIF… Expand
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2003
2003
Pharmacological characterisation of native somatostatin receptors in AtT-20 mouse tumour corticotrophs.
1. The mouse corticotroph tumour cell line AtT-20 is a useful model to investigate the physiological role of native somatostatin… Expand
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2003
2003
Native somatostatin sst2 and sst5 receptors functionally coupled to Gi/o-protein, but not to the serum response element in AtT-20 mouse tumour corticotrophs
Of the five cloned somatostatin (SRIF: somatotropin release inhibitory factor) receptors (sst1–5), only sst2 and sst5 receptors… Expand
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2001
2001
Identification of the somatostatin receptor subtypes involved in regulation of growth hormone secretion in chickens
The effects of somatostatin (SRIF) are mediated through five distinct G-protein-coupled receptors (SSTR1-5). In the present study… Expand
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Highly Cited
2000
Highly Cited
2000
Somatostatin inhibits insulin and glucagon secretion via two receptors subtypes: an in vitro study of pancreatic islets from somatostatin receptor 2 knockout mice.
Somatostatin (SST) potently inhibits insulin and glucagon release from pancreatic islets. Five distinct membrane receptors (SSTR1… Expand
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Highly Cited
2000
Highly Cited
2000
Somatostatin Inhibits Insulin and Glucagon Secretion via Two Receptor Subtypes: An in Vitro Study of Pancreatic Islets from Somatostatin Receptor 2 Knockout Mice.
Somatostatin (SST) potently inhibits insulin and glucagon release from pancreatic islets. Five distinct membrane receptors (SSTR1… Expand
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