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L 700462

Known as: L-700,462, L-700462 
 
National Institutes of Health

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Broader (1)

tirofiban

Papers overview

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2005
2005
1512 MK-383 ( L-700 , 462 ) , a Selective Nonpeptide Platelet Glycoprotein 1 Ib / IIIa Antagonist , Is Active in Man
Background. Fibrinogen-dependent cross-linking of glycoprotein (GP) lIb/IIIa on activated platelets is the final mechanism… Expand
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2000
2000
Integrin a IIb b 3 Inhibitor Preserves Microvascular Patency in Experimental Acute Focal Cerebral Ischemia
39. Theroux P, Kouz S, Knudtson ML, Kells C, Nasmith J, Roy L, Ave S. D., Steiner B, Xiao Z, Rapold HJ. A randomized double-blind… Expand
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Highly Cited
1993
Highly Cited
1993
MK-383 (L-700,462), a selective nonpeptide platelet glycoprotein IIb/IIIa antagonist, is active in man.
BACKGROUND Fibrinogen-dependent cross-linking of glycoprotein (GP) IIb/IIIa on activated platelets is the final mechanism leading… Expand
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  • figure 4
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1993
1993
The effects of two synthetic glycoprotein IIb/IIIa antagonists, Ro 43-8857 and L-700,462, on platelet aggregation and bleeding in guinea-pigs and dogs: evidence that Ro 43-8857 is orally active.
In vitro platelet aggregation studies in whole blood were used to define the species-specificity profile of two synthetic GP-IIb… Expand
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