FAQ

L 693989

Known as: L-693,989, L-Proline, N2-(10,12-dimethyl-1-oxotetradecyl)-(4R,5R)-4,5-dihydroxy-L-ornithyl-L-threonyl-trans-4-hydroxy-L-prolyl-(S)-4-hydroxy-4-(4-(phosphonooxy)phenyl)-L-threonyl-threo-3-hydroxy-L-glutaminyl-3-hydroxy-, cyclic (6-1)-peptide, monosodium salt, 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

1992-2010
01219922010

Related topics

Related topics

1 relation

Broader (1)

Cyclic Peptides

Related mentions per year

Related mentions per year

1955-2018
1960198020002020
L 693989
Cyclic Peptides

Papers overview

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2010
2010
Evidence for DNA synthesis in Pneumocystis carinii trophozoites treated with the beta-1,3-glucan synthesis inhibitor pneumocandin L-693,989.
Pneumocandins inhibit beta-1,3-glucan synthesis preventing the development of Pneumocystis cysts that are absent from the lungs… (More)
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1995
1995
Aerosol and parenteral pneumocandins are effective in a rat model of pulmonary aspergillosis.
The pneumocandins are semisynthetic analogs of echinocandin-like compounds that have shown efficacy in animal models of systemic… (More)
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Highly Cited
1994
Highly Cited
1994
Morphological effects of lipopeptides against Aspergillus fumigatus correlate with activities against (1,3)-beta-D-glucan synthase.
The lipopeptide antifungal agents, echinocandins, papulacandins, and pneumocandins, kill Candida albicans by inhibiting glucan… (More)
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1994
1994
Aerosolized L-693,989 for Pneumocystis carinii prophylaxis in rats.
Water-soluble pneumocandin L-693,989, a potent antipneumocystis agent in the rat model for Pneumocystis carinii pneumonia (PCP… (More)
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1992
1992
Antipneumocystis activity of water-soluble lipopeptide L-693,989 in rats.
Water-soluble lipopeptide L-693,989 was evaluated for its antipneumocystis activity in rats. Rats from colonies with latent… (More)
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