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L 658758
Known as:
L 658,758
, L-658,758
, L-658758
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National Institutes of Health
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Related topics
Related topics
2 relations
Broader (2)
Cephalosporins
Serine Proteinase Inhibitors
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2008
2008
ROLE OF NEUTROPHIL ELASTASE IN DEVELOPMENT OF PULMONARY VASCULAR INJURY AND SEPTIC SHOCK IN RATS
N. Harada
,
K. Okajima
,
H. Isobe
Shock
2008
Corpus ID: 25239175
Prostacyclin prevents pulmonary vascular injury and shock by inhibiting increases in lung tissue levels of TNF in rats…
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1998
1998
Neutrophil elastase promotes lung microvascular injury and proteolysis of endothelial cadherins
D. Carden
,
F. Xiao
,
C. Moak
,
B. H. Willis
,
Sherry Robinson-Jackson
,
Steve Alexander
1998
Corpus ID: 31741100
Carden, D., F. Xiao, Candace Moak, Bradley H. Willis, Sherry Robinson-Jackson, and SteveAlexander. Neutrophil elastase promotes…
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1997
1997
Inhibition of neutrophil elastase in CF sputum by L-658,758.
D. Rees
,
J. Brain
,
M. Wohl
,
J. Humes
,
R. Mumford
Journal of Pharmacology and Experimental…
1997
Corpus ID: 10551391
Elastases in cystic fibrosis (CF) pulmonary fluids damage lung tissue and perpetuate cycles of infection, inflammation and injury…
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1997
1997
Role of granulocyte elastase in indomethacin-induced gastric mucosal lesion formation in rats.
K. Murakami
,
K. Okajima
,
+4 authors
K. Takatsuki
Journal of Laboratory and Clinical Medicine
1997
Corpus ID: 34836854
1996
1996
Protease inhibition attenuates microvascular dysfunction in postischemic skeletal muscle.
D. Carden
,
R. Korthuis
American Journal of Physiology
1996
Corpus ID: 13503154
Neutrophils accumulate in skeletal muscle subjected to ischemia-reperfusion and appear to contribute to reperfusion-induced…
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1995
1995
Formation of polymorphonuclear leukocyte elastase: alpha 1 proteinase inhibitor complex and A alpha (1-21) fibrinopeptide in human blood stimulated with the calcium ionophore A23187. A model to…
S. Pacholok
,
P. Davies
,
+4 authors
J. Humes
Biochemical Pharmacology
1995
Corpus ID: 35380673
1995
1995
An inhibitor of leukocyte elastase prevents immune complex-mediated hemorrhage in the rat lung.
D. Fletcher
,
D. Osinga
,
+5 authors
P. Davies
Journal of Pharmacology and Experimental…
1995
Corpus ID: 43383932
The typical reverse passive Arthus reaction (RPA) was attained in rats by the instillation of a rabbit antiovalbumin serum into…
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1995
1995
Antiproteases modulate bronchial epithelial cell responses to endotoxin.
S. Koyama
,
S. Rennard
,
L. Claassen
,
R. Robbins
American Journal of Pathology
1995
Corpus ID: 2790621
Escherichia coli endotoxin (0.1 to 1000 micrograms/ml) stimulated the release of neutrophil chemotactic activity (P < 0.001) and…
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1992
1992
Inhibition of human leukocyte elastase. 4. Selection of a substituted cephalosporin (L-658,758) as a topical aerosol.
P. Finke
,
S. K. Shah
,
+7 authors
P. Davies
Journal of Medicinal Chemistry
1992
Corpus ID: 42614451
Human leukocyte elastase (HLE) is a serine protease which has been implicated as a causative agent in several pulmonary diseases…
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