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Kinesin-1 Heavy Chain
Known as:
Conventional Kinesin Heavy Chain
, Kinesin Heavy Chain
, Ubiquitous Kinesin Heavy Chain
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Kinesin-1 heavy chain (963 aa, ~110 kDa) is encoded by the human KIF5B gene. This protein is involved in organelle and vesicle transport.
National Institutes of Health
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Related topics
Related topics
8 relations
Cellular Membrane
Intracellular Transport
KIF5B gene
Ligand Binding
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2016
Highly Cited
2016
Microtubule–microtubule sliding by kinesin-1 is essential for normal cytoplasmic streaming in Drosophila oocytes
Wen Lu
,
Michael Winding
,
M. Lakonishok
,
Jill Wildonger
,
Vladimir Gelfand
Proceedings of the National Academy of Sciences
2016
Corpus ID: 24049300
Significance Generation of mechanical forces by molecular motors is essential for development. Previously, we showed that the…
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Highly Cited
2016
Highly Cited
2016
Role of kinesin-1–based microtubule sliding in Drosophila nervous system development
Michael Winding
,
Michael T Kelliher
,
Wen Lu
,
Jill Wildonger
,
Vladimir Gelfand
Proceedings of the National Academy of Sciences
2016
Corpus ID: 41003833
Significance We previously demonstrated that the microtubule (MT) motor protein kinesin-1 slides and transports MTs themselves in…
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2014
2014
Hospital Affiliations, Co-Branding, and Consumer Impact
W. Gombeski
,
Joseph O Claypool
,
+5 authors
Jan Taylor
Health Marketing Quarterly
2014
Corpus ID: 8118002
Alliances, affiliations, and partnerships continue to grow as one way for health care organizations to better serve their…
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Highly Cited
2010
Highly Cited
2010
Kinesin-1 heavy chain mediates microtubule sliding to drive changes in cell shape
A. L. Jolly
,
H. Kim
,
D. Srinivasan
,
M. Lakonishok
,
A. Larson
,
Vladimir Gelfand
Proceedings of the National Academy of Sciences
2010
Corpus ID: 205248818
Microtubules are typically observed to buckle and loop during interphase in cultured cells by an unknown mechanism. We show that…
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Highly Cited
2009
Highly Cited
2009
The Processivity of Kinesin-2 Motors Suggests Diminished Front-Head Gating
Gayatri Muthukrishnan
,
Yangrong Zhang
,
Shankar Shastry
,
W. Hancock
Current Biology
2009
Corpus ID: 17596585
2008
2008
Kinesin‐1 (uKHC/KIF5B) is Required for Bidirectional Motility of ER Exit Sites and Efficient ER‐to‐Golgi Transport
Vijay R. Gupta
,
K. Palmer
,
P. Spence
,
A. Hudson
,
D. Stephens
Traffic : the International Journal of…
2008
Corpus ID: 43564578
Transport of proteins and lipids between intracellular compartments is fundamental to the organization and function of eukaryotic…
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Highly Cited
2006
Highly Cited
2006
Cargo selection by specific kinesin light chain 1 isoforms
M. Woźniak
,
V. Allan
EMBO Journal
2006
Corpus ID: 24223343
Kinesin‐1 drives the movement of diverse cargoes, and it has been proposed that specific kinesin light chain (KLC) isoforms…
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Highly Cited
2002
Highly Cited
2002
Herpes Simplex Virus Tegument Protein US11 Interacts with Conventional Kinesin Heavy Chain
R. Diefenbach
,
M. Miranda-Saksena
,
+4 authors
A. Cunningham
Journal of Virology
2002
Corpus ID: 10326454
ABSTRACT Little is known about the mechanisms of transport of neurotropic herpesviruses, such as herpes simplex virus (HSV…
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Highly Cited
2002
Highly Cited
2002
The heavy chain of conventional kinesin interacts with the SNARE proteins SNAP25 and SNAP23.
R. Diefenbach
,
E. Diefenbach
,
M. Douglas
,
A. Cunningham
Biochemistry
2002
Corpus ID: 25557559
Recent studies on the conventional motor protein kinesin have identified a putative cargo-binding domain (residues 827-906…
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2000
2000
Expression and partial characterization of kinesin-related proteins in differentiating and adult skeletal muscle.
L. M. Ginkel
,
L. Wordeman
Molecular Biology of the Cell
2000
Corpus ID: 9479532
Using pan-kinesin antibodies to screen a differentiating C2C12 cell library, we identified the kinesin proteins KIF3A, KIF3B, and…
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