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Ketol-acid reductoisomerase

Known as: Isomeroreductase, Dihydroxyisovalerate Dehydrogenase (Isomerizing), Alpha-Acetohydroxyacid Isomeroreductase 
An enzyme that catalyzes the oxidation of (R)-2,3-dihydroxy-3-methylbutanoate to (S)-2-hydroxy-2-methyl-3-oxobutanoate in the presence of NADP. It is… 
National Institutes of Health

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In BloodProcess of secretionantagonists & inhibitorsaspects of radiation effects

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2004
2004
Crystal structure of 1-deoxy-d-xylulose-5-phosphate reductoisomerase from Zymomonas mobilis at 1.9-A resolution.
2003
2003
Role of the Non‐Mevalonate Pathway in Indole Alkaloid Production by Catharanthus roseus Hairy Roots
The 1‐deoxy‐d‐xylulose‐5‐phosphate (DXP) pathway (non‐mevalonate pathway) leading to terpenoids via isopentenyl diphosphate (IPP… 
Highly Cited
2002
Highly Cited
2002
Isoprenoid Biosynthesis in Synechocystis sp. Strain PCC6803 Is Stimulated by Compounds of the Pentose Phosphate Cycle but Not by Pyruvate or Deoxyxylulose-5-Phosphate
ABSTRACT The photosynthetic cyanobacterium Synechocystis sp. strain PCC6803 possesses homologs of known genes of the non… 
2000
2000
Biased distribution of the branched-chain fatty acids in ceramides of vernix caseosa
The compositions of ester- and amide-linked fatty acids from ceramides of human vernix caseosa were described with emphasis on… 
2000
2000
A potential target enzyme for trypanocidal drugs revealed by the crystal structure of NAD-dependent glycerol-3-phosphate dehydrogenase from Leishmania mexicana.
1999
1999
Stereochemistry of the reduction step mediated by recombinant 1-deoxy-D-xylulose 5-phosphate isomeroreductase.
[formula: see text] The stereochemistry of the 1-deoxy-D-xylulose 5-phosphate (DXP) isomeroreductase reduction step has been… 
1999
1999
Characterization of the conformational changes of acetohydroxy acid isomeroreductase induced by the binding of Mg2+ ions, NADPH, and a competitive inhibitor.
Acetohydroxy acid isomeroreductase (EC 1.1.1.86), the second enzyme of the parallel branched chain amino acid pathway, is a… 
1994
1994
Interactions of plant acetohydroxy acid isomeroreductase with reaction intermediate analogues: correlation of the slow, competitive, inhibition kinetics of enzyme activity and herbicidal effects.
N-Hydroxy-N-isopropyloxamate (IpOHA) is known to inhibit extremely tightly (Ki of 22 pM) the bacterial acetohydroxy acid… 
1973
1973
Isoleucine and Valine Metabolism in Escherichia coli XXI. Mutations Affecting Derepression and Valine Resistance
The activity of acetohydroxy acid isomeroreductase, an essential enzyme for isoleucine and valine biosynthesis in Escherichia… 
Highly Cited
1969
Highly Cited
1969
The metabolism of valine and isoleucine in Escherichia coli. XVII. The role of induction in the derepression of acetohydroxy acid isomeroreductase.
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