FAQ

Kainic Acid

Known as: 3-Pyrrolidineacetic acid, 2-carboxy-4-(1-methylethenyl)-, (2S-(2alpha,3beta,4beta))-, Acid, Digenic, 2-Carboxy-4-isopropenyl-3-pyrrolidineacetic Acid 
(2S-(2 alpha,3 beta,4 beta))-2-Carboxy-4-(1-methylethenyl)-3-pyrrolidineacetic acid. Ascaricide obtained from the red alga Digenea simplex. It is a… (More)

Topic mentions per year

Topic mentions per year

1957-2018
010020019572017

Related topics

Related topics

22 relations

Narrower (8)

1'-hydroxykainic acidKainateacromelic acid Aacromelic acid B
(More)

Broader (3)

AcidsAntinematodal AgentsExcitatory Amino Acid Agonists
Glutamic AcidIn BloodNeurotoxinsReceptors, Kainic Acid
(More)

Related mentions per year

Related mentions per year

1936-2018
19401960198020002020
Kainic Acid
Glutamic Acid
agonists
Acids
Neurotoxins
Kainate

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2006
Highly Cited
2006
Suppression of Reactive Oxygen Species and Neurodegeneration by the PGC-1 Transcriptional Coactivators
PPARgamma coactivator 1alpha (PGC-1alpha) is a potent stimulator of mitochondrial biogenesis and respiration. Since the… (More)
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Highly Cited
2003
Highly Cited
2003
CB1 cannabinoid receptors and on-demand defense against excitotoxicity.
Abnormally high spiking activity can damage neurons. Signaling systems to protect neurons from the consequences of abnormal… (More)
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Highly Cited
2001
Highly Cited
2001
Erythropoietin prevents neuronal apoptosis after cerebral ischemia and metabolic stress.
Erythropoietin (EPO) promotes neuronal survival after hypoxia and other metabolic insults by largely unknown mechanisms… (More)
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Highly Cited
1999
Highly Cited
1999
Hippocampal and entorhinal cortex high-frequency oscillations (100--500 Hz) in human epileptic brain and in kainic acid--treated rats with chronic seizures.
PURPOSE Properties of oscillations with frequencies >100 Hz were studied in kainic acid (KA)-treated rats and compared with those… (More)
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Highly Cited
1998
Highly Cited
1998
Kainic acid increases the proliferation of granule cell progenitors in the dentate gyrus of the adult rat.
Granule cell progenitors in the dentate gyrus of the hippocampal formation have the unusual capacity to be able to divide in the… (More)
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Highly Cited
1997
Highly Cited
1997
Absence of excitotoxicity-induced apoptosis in the hippocampus of mice lacking the Jnk3 gene.
Excitatory amino acids induce both acute membrane depolarization and latent cellular toxicity, which often leads to apoptosis in… (More)
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Highly Cited
1987
Highly Cited
1987
Permeation and block of N-methyl-D-aspartic acid receptor channels by divalent cations in mouse cultured central neurones.
1. Spinal cord and hippocampal neurones in cell culture were voltage clamped using the tight-seal, whole-cell recording technique… (More)
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Highly Cited
1985
Highly Cited
1985
Evidence of functional mossy fiber sprouting in hippocampal formation of kainic acid-treated rats.
In the rat hippocampal formation, degeneration of CA4-derived afferent fibers provokes the growth of mossy fiber collaterals into… (More)
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Highly Cited
1984
Highly Cited
1984
Kainic-acid-induced seizures: a developmental study.
Developmental dose-response curves for kainic-acid-induced seizures were generated in rats. Rats at 15-18 days (pups), 33-37 days… (More)
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Highly Cited
1983
Highly Cited
1983
Kainic acid induced seizures: neurochemical and histopathological changes.
Behavioural, histopathological and neurochemical changes induced by systemic injection of kainic acid (10 mg/kg, s.c.) were… (More)
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