Kainate

The small ubiquitin-like modifier protein (SUMO) regulates transcriptional activity and the translocation of proteins across the… (More)

The ability of synapses to modify their synaptic strength in response to activity is a fundamental property of the nervous system… (More)

L-glutamate, the neurotransmitter of the majority of excitatory synapses in the brain, acts on three classes of ionotropic… (More)

Little is known of the molecular mechanisms that trigger oligodendrocyte death and demyelination in many acute central nervous… (More)

L-Glutamate, the principal excitatory neurotransmitter in the vertebrate central nervous system, acts on three classes of… (More)

Glutamate, the neurotransmitter at most excitatory synapses in the brain, activates a variety of receptor subtypes that can… (More)

Using microcultured neurons and hippocampal slices, we found that under conditions that completely block AMPA receptors, kainate… (More)

CA2+-permeable glutamate receptors assembled from subunits containing a GLN residue at the RNA editing site in membrane domain 2… (More)

Potentiation by cyclothiazide of recombinant glutamate receptor responses in Xenopus oocytes showed absolute selectivity for AMPA… (More)

In whole-cell recordings from mammalian CNS neurons, AMPA-preferring glutamate receptors exhibit strong desensitization in… (More)