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KW-2450
Known as:
IGF-1R/IR Inhibitor KW-2450
An orally bioavailable inhibitor of insulin-like growth factor 1 receptor (IGF-1R) and insulin receptor (IR) tyrosine kinases with potential…
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National Institutes of Health
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Related topics
Related topics
3 relations
Broader (2)
Indazoles
Piperazines
Receptor Tyrosine Kinase Inhibition
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2015
2015
Antitumor Activity of KW-2450 against Triple- NegativeBreastCancerbyInhibitingAuroraAand
K. Kai
,
Kimie Kondo
,
+11 authors
N. Ueno
2015
Corpus ID: 89667148
Currently, no targeted drug is available for triple-negative breast cancer (TNBC), an aggressive breast cancer that does not…
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2011
2011
Abstract 3605: KW-2450, a novel orally-active dual IGF1R/IR inhibitor: Antitumor effects in vitro and in vivo
Y. Maekawa
,
Fumito Koizumi
,
+11 authors
S. Soga
2011
Corpus ID: 72778784
Proceedings: AACR 102nd Annual Meeting 2011‐‐ Apr 2‐6, 2011; Orlando, FL KW-2450 is an orally active, multi-kinase inhibitor…
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