KU 60019

Known as: KU-60019, KU60019 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

2009-2017
02420092017

Papers overview

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2017
2017
Senescence, defined as irreversible cell-cycle arrest, is the main driving force of aging and age-related diseases. Here, we… (More)
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2017
2017
Nanoparticle (NP) chemotherapeutics can improve the therapeutic index of chemoradiotherapy (CRT). However, the effect of NP… (More)
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2015
2015
We have recently reported that glioblastoma (GB)-initiating cells (GIC) with low expression and/or mutation of TP53 and high… (More)
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2015
2015
Ataxia telangiectasia mutated (ATM) is an important signaling molecule in the DNA damage response (DDR). ATM loss of function can… (More)
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2014
2014
We have previously shown that pharmacological inhibition of ataxia telangiectasia mutated (ATM) protein sensitizes glioblastoma… (More)
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2014
2014
It has previously been reported that KU60019, as a highly effective radiosensitizer, inhibits the DNA damage response and blocks… (More)
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2013
2013
PURPOSE Glioblastoma multiforme (GBM) is the most lethal form of brain cancer with a median survival of only 12 to 15 months… (More)
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2012
2012
Glioblastoma multiforme (GBM) is notoriously resistant to treatment. Therefore, new treatment strategies are urgently needed. ATM… (More)
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2012
2012
Previous studies have shown that tumor-driving glioma stem cells (GSC) may promote radio-resistance by constitutive activation of… (More)
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Highly Cited
2009
Highly Cited
2009
Ataxia telangiectasia (A-T) mutated (ATM) is critical for cell cycle checkpoints and DNA repair. Thus, specific small molecule… (More)
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