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KU 60019

Known as: KU-60019, KU60019 
 
National Institutes of Health

Papers overview

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2019
2019
Despite advances in glioblastoma (GBM) therapy, prognosis of the disease remains poor with a low survival rate. Cannabidiol (CBD… Expand
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2017
2017
Senescence, defined as irreversible cell-cycle arrest, is the main driving force of aging and age-related diseases. Here, we… Expand
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2015
2015
Ataxia telangiectasia mutated (ATM) is an important signaling molecule in the DNA damage response (DDR). ATM loss of function can… Expand
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2015
2015
We have recently reported that glioblastoma (GB)-initiating cells (GIC) with low expression and/or mutation of TP53 and high… Expand
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2015
2015
In this study, the involvement of ataxia telangiectasia mutated (ATM) kinase and heat shock protein 90 (HSP90) in endothelial… Expand
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2014
2014
We have previously shown that pharmacological inhibition of ataxia telangiectasia mutated (ATM) protein sensitizes glioblastoma… Expand
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Highly Cited
2013
Highly Cited
2013
Purpose: Glioblastoma multiforme (GBM) is the most lethal form of brain cancer with a median survival of only 12 to 15 months… Expand
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Highly Cited
2012
Highly Cited
2012
Glioblastoma multiforme (GBM) is notoriously resistant to treatment. Therefore, new treatment strategies are urgently needed. ATM… Expand
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2012
2012
Previous studies have shown that tumor-driving glioma stem cells (GSC) may promote radio-resistance by constitutive activation of… Expand
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Highly Cited
2009
Highly Cited
2009
Ataxia telangiectasia (A-T) mutated (ATM) is critical for cell cycle checkpoints and DNA repair. Thus, specific small molecule… Expand
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