KRAS NP_004976.2:p.G12D

Known as: KRAS p.G12D, KRAS G12D, KRAS NP_004976.2:p.Gly12Asp 
A change in the amino acid residue at position 12 in the GTPase KRas protein where glycine has been replaced by aspartic acid.

Topic mentions per year

Topic mentions per year

1999-2018
051019992018

Papers overview

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Highly Cited
2016
Highly Cited
2016
We identified a polyclonal CD8+ T-cell response against mutant KRAS G12D in tumor-infiltrating lymphocytes obtained from a… (More)
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2016
2016
Objectives:There is no molecular biomarker available in the clinical practice to assess the prognosis of advanced pancreatic… (More)
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Highly Cited
2015
Highly Cited
2015
Intra-tumoral genetic and functional heterogeneity correlates with cancer clinical prognoses. However, the mechanisms by which… (More)
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2013
2013
The rapid development of molecular biology techniques allows for the introduction of real-time polymerase chain reaction (PCR… (More)
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2013
2013
BACKGROUND The issue of whether patients diagnosed with metastatic colorectal cancer who harbor KRAS codon 13 mutations could… (More)
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2013
2013
Acute T-cell lymphoblastic leukemia/lymphoma (T-ALL) is an aggressive hematopoietic malignancy affecting both children and adults… (More)
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2010
2010
Confounding effects of specific KRAS gene alterations on colorectal cancer (CRC) prognosis stratified by microsatellite… (More)
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2010
2010
A 77-year-old man who had undergone resection of the descending colon, the sixth hepatic segment, and peritoneal biopsy… (More)
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2008
2008
KRAS and BRAF mutations appear of relevance in the genesis and progression of several solid tumor types but the co-occurrence and… (More)
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2007
2007
There is a compelling need to image pancreas cancer at an early stage. Human pancreas cancer cells display elevated levels of… (More)
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