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KRAS NP_004976.2:p.G12D

Known as: KRAS p.G12D, KRAS G12D, KRAS NP_004976.2:p.Gly12Asp 
A change in the amino acid residue at position 12 in the GTPase KRas protein where glycine has been replaced by aspartic acid.
National Institutes of Health

Papers overview

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2019
2019
Objective: To established Apc(loxp/loxp)+Kras(LSL-G12D/-)+Smad4(loxp/loxp) transgenic mouse model that mimick the occurrence and… 
2019
2019
Pancreatic ductal adenocarcinoma (PDA) is the most deadly disease in human malignancies. Using pancreatic organoid models, we… 
2017
2017
Pancreatic ductular adenocarcinoma (PDAC) ranks fourth as a cause of cancer death in the USA and is almost universally fatal… 
2015
2015
Dendritic cells (DCs) are powerful APCs that can induce Ag-specific adaptive immune responses and are increasingly recognized as… 
2013
2013
or mice carrying activated ErbB2 (Neu), a model of breast cancer, to Hk2 conditional knockout mice. They found that the average… 
2013
2013
weight matrix models for binding affini-ties based on analysis of data from chromatin immunoprecipitation and sequencing (ChIP… 
2013
2013
Background: Pancreatic cancer, an aggressive and lethal cancer is the fourth leading cause of cancer-related deaths in the United… 
2012
2012
Lung cancer is the leading cause of cancer deaths worldwide, and current therapies fail to treat this disease in the vast… 
2012
2012
Human pancreatic ductal adenocarcinoma (PDAC) displays high heterogeneity in terms of morphology, onset, and therapy response… 
2012
2012
Lung cancer is the leading cause of cancer deaths worldwide, and current therapies fail to treat this disease in the vast…