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KPU-300

National Institutes of Health

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2 relations

Broader (2)

BenzophenonesDiketopiperazines

Papers overview

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2017
2017
Click strategy using disodium salts of amino acids improves the water solubility of plinabulin and KPU-300.
Plinabulin and KPU-300 are promising anti-microtubule agents; however, the low water solubility of these compounds (<0.1µg/mL… Expand
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2016
2016
KPU-300, a novel benzophenone-diketopiperazine-type anti-microtubule agent with a 2-pyridyl structure, is a potent radiosensitizer that synchronizes the cell cycle in early M phase
2015
2015
KPU-300, a Novel Benzophenone–Diketopiperazine–Type Anti-Microtubule Agent with a 2-Pyridyl Structure, Is a Potent Radiosensitizer That Synchronizes the Cell Cycle in Early M Phase
KPU-300 is a novel colchicine-type anti-microtubule agent derived from plinabulin (NPI-2358). We characterized the effects of KPU… Expand
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2015
2015
A novel benzophenone-diketopiperadine-type anti-microtubule agent with a 2-pyridine structure, KPU-300, is a potent radiosensitizer through synchronization of the cell cycle at M-phase
2014
2014
Development of a new benzophenone-diketopiperazine-type potent antimicrotubule agent possessing a 2-pyridine structure.
A new benzophenone-diketopiperazine-type potent antimicrotubule agent was developed by modifying the structure of the clinical… Expand
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