KN 62

Known as: 5-Isoquinolinesulfonic acid, 4-(2-((5-isoquinolinylsulfonyl)methylamino)-3-oxo-3-(4-phenyl-1-piperazinyl)propyl)phenyl ester, (S)-, KN-62, KN62 compound 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

1990-2018
0204019902018

Papers overview

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Highly Cited
2008
Highly Cited
2008
Pannexin 1 (Panx1), an ortholog to invertebrate innexin gap junctions, has recently been proposed to be the pore induced by P2X(7… (More)
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1999
1999
We have shown previously that activation of mGlu receptors using a group I specific mGlu receptor agonist, (R,S)-3,5… (More)
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Highly Cited
1997
Highly Cited
1997
Long-term potentiation (LTP), a cellular model of learning and memory, requires calcium-dependent protein kinases. Induction of… (More)
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Highly Cited
1997
Highly Cited
1997
1. Extracellular adenosine 5'-triphosphate (ATP) is an agonist for a P2Z receptor on human lymphocytes which mediates opening of… (More)
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1995
1995
We have used monolayers of parental 3T3 fibroblasts and 3T3 cells expressing transfected cell adhesion molecules (CAMs, NCAM, N… (More)
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1994
1994
Expression of immediate early genes and phosphorylation of the transcription factor CREB are induced in the suprachiasmatic… (More)
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1992
1992
Cholinergic stimulation of parietal cell secretion is mediated by an increase in intracellular calcium. KN-62, a selective… (More)
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1992
1992
The effects of KN-62, a specific inhibitor of Ca2+/calmodulin-dependent protein kinase II (CamPKII), on insulin secretion and… (More)
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Highly Cited
1991
Highly Cited
1991
We reported that one of the isoquinolinesulfonamide derivatives, KN-62, is a potent and specific inhibitor of Ca2+/calmodulin… (More)
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Highly Cited
1990
Highly Cited
1990
1-[N,O-Bis(5-isoquinolinesulfonyl)-N-methyl-L-tyrosyl]-4-phenylpipera zine (KN-62), a selective inhibitor of rat brain Ca2… (More)
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