KN 62

Pannexin 1 (Panx1), an ortholog to invertebrate innexin gap junctions, has recently been proposed to be the pore induced by P2X(7… (More)

We have shown previously that activation of mGlu receptors using a group I specific mGlu receptor agonist, (R,S)-3,5… (More)

Long-term potentiation (LTP), a cellular model of learning and memory, requires calcium-dependent protein kinases. Induction of… (More)

1. Extracellular adenosine 5'-triphosphate (ATP) is an agonist for a P2Z receptor on human lymphocytes which mediates opening of… (More)

We have used monolayers of parental 3T3 fibroblasts and 3T3 cells expressing transfected cell adhesion molecules (CAMs, NCAM, N… (More)

Expression of immediate early genes and phosphorylation of the transcription factor CREB are induced in the suprachiasmatic… (More)

Cholinergic stimulation of parietal cell secretion is mediated by an increase in intracellular calcium. KN-62, a selective… (More)

The effects of KN-62, a specific inhibitor of Ca2+/calmodulin-dependent protein kinase II (CamPKII), on insulin secretion and… (More)

We reported that one of the isoquinolinesulfonamide derivatives, KN-62, is a potent and specific inhibitor of Ca2+/calmodulin… (More)

1-[N,O-Bis(5-isoquinolinesulfonyl)-N-methyl-L-tyrosyl]-4-phenylpipera zine (KN-62), a selective inhibitor of rat brain Ca2… (More)