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KMT2E gene

Known as: Lysine (K)-Specific Methyltransferase 2E Gene, lysine methyltransferase 2E, HDCMC04P 
This gene is involved in transcriptional regulation, cell cycle progression and protein methylation.
National Institutes of Health

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MLL5 wt Allele
MethylationNegative Regulation of Cell CycleProtein methylationTranscriptional Regulation

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2020
2020
CRISPR/Cas9-mediated knockout of MLL5 enhances apoptotic effect of cisplatin in HeLa cells in vitro
Mixed lineage leukemia 5 (MLL5) transactivates the expression of E6 and E7 oncogenes in cervical cancer cells. In this study, we… 
2017
2017
KMT2E-ASNS: a novel relapse-specific fusion gene in early T-cell precursor acute lymphoblastic leukemia.
To the editor: Early T-cell precursor acute lymphoblastic leukemia (ETP-ALL) is a recently characterized subtype accounting for… 
2016
2016
MLL5 limits PLK1 aggregation
< a d d a r t t y p e = " r e l " d o i = " 1 0. 1 0 8 3 / j c b. 2 0 1 5 0 1 0 2 1 " > Zhao et al.< / a d d a r t > reveal that… 
2014
2014
Association of the histone-lysine N-methyltransferase MLL5 gene with coronary artery disease in Chinese Han people
2014
2014
Prognostic impact of KMT2E transcript levels on outcome of patients with acute promyelocytic leukaemia treated with all‐trans retinoic acid and anthracycline‐based chemotherapy: an International…
The KMT2E (MLL5) gene encodes a histone methyltransferase implicated in the positive control of genes related to haematopoiesis… 
2012
2012
The SET Domain Protein, Set3p, Promotes the Reliable Execution of Cytokinesis in Schizosaccharomyces pombe
In response to perturbation of the cell division machinery fission yeast cells activate regulatory networks that ensure the… 
2012
2012
MLL5 maintains genomic integrity by regulating the stability of the chromosomal passenger complex through a functional interaction with Borealin
Summary Mixed lineage leukemia 5 (MLL5) is a versatile nuclear protein associated with many cellular events. We have shown… 
2012
2012
A conserved histone deacetylase with a role in the regulation of cytokinesis in Schizosaccharomyces pombe
BackgroundIn Schizosaccharomyces pombe the SET domain protein, Set3p - together with its interacting partners, Snt1p, and Hif2p… 
2012
2012
A conserved histone deacetylase with a role in the regulation of cytokinesis in Schizosaccharomyces pombe
In Schizosaccharomyces pombe the SET domain protein, Set3p - together with its interacting partners, Snt1p, and Hif2p - form a… 
2012
2012
Aberrant expression of the MLL5, BAALC, ID1, and WT1 genes is associated with higher induction mortality and poorer overall survival in acute promyelocytic leukemia patients treated with atra and…
Abstract 1407 [][1] Background: Aberrant expression of MLL5 , BAALC , ID1, and WT1 genes is frequently associated with inferior… 
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