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KMT2E gene

Known as: Lysine (K)-Specific Methyltransferase 2E Gene, lysine methyltransferase 2E, HDCMC04P 
This gene is involved in transcriptional regulation, cell cycle progression and protein methylation.
National Institutes of Health

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MLL5 wt Allele
MethylationNegative Regulation of Cell CycleProtein methylationTranscriptional Regulation

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
MLL5 limits PLK1 aggregation
< a d d a r t t y p e = " r e l " d o i = " 1 0. 1 0 8 3 / j c b. 2 0 1 5 0 1 0 2 1 " > Zhao et al.< / a d d a r t > reveal that… 
2016
2016
MLL5 Promotes Self-Renewing Glioblastoma Growth via H3.3 Suppression.
In adult GBM, MLL5 reduces H3.3 occupancy, globally reorganizes chromatin, and promotes self-renewal. 
2014
2014
Small Molecule Therapeutics Targeted Silencing of MLL 5 b Inhibits Tumor Growth and Promotes Gamma-Irradiation Sensitization in HPV 16 / 18-Associated Cervical Cancers
We previously identified a novel MLL5 isoform, MLL5b, which was essential for E6 and E7 transcriptional activation in HPV16/18… 
2006
2006
Functional genetics of hereditary and sporadic uterine leiomyomas
Uterine leiomyomas (fibroids) are common benign neoplasms arising from the smooth muscle layer of the uterus, the myometrium… 
2002
2002
Rapid identification of frequent MLL rearrangements in hematolgic malignancies by multiplex RT-PCR in a single assay
Rapid identification of frequent MLL rearrangements in hematolgic malignancies by multiplex RT-PCR in a single assay 
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