KMT2D gene

Known as: MYELOID/LYMPHOID OR MIXED LINEAGE LEUKEMIA 2, LYSINE-SPECIFIC METHYLTRANSFERASE 2D, MYELOID/LYMPHOID OR MIXED LINEAGE LEUKEMIA 4 
This gene plays a role in co-activation of gene expression.

Topic mentions per year

Topic mentions per year

1999-2018
0204019992018

Papers overview

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2016
2016
The transcriptional shift from repression to activation of target genes is crucial for the fidelity of Notch responses through… (More)
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2015
2015
The gene encoding the lysine-specific histone methyltransferase KMT2D has emerged as one of the most frequently mutated genes in… (More)
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2015
2015
Mutations in the gene encoding the KMT2D (or MLL2) methyltransferase are highly recurrent and occur early during tumorigenesis in… (More)
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Highly Cited
2014
Highly Cited
2014
Esophageal squamous cell carcinoma (ESCC) is one of the deadliest cancers. We performed exome sequencing on 113 tumor-normal… (More)
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Highly Cited
2014
Highly Cited
2014
Follicular lymphoma is an incurable malignancy, with transformation to an aggressive subtype representing a critical event during… (More)
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Highly Cited
2014
Highly Cited
2014
Esophageal squamous cell carcinoma (ESCC) is prevalent worldwide and particularly common in certain regions of Asia. Here we… (More)
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Highly Cited
2014
Highly Cited
2014
Oesophageal cancer is one of the most aggressive cancers and is the sixth leading cause of cancer death worldwide. Approximately… (More)
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Highly Cited
2013
Highly Cited
2013
Histone H3 lysine 4 (H3K4) can be mono-, di-, and trimethylated by members of the COMPASS (complex of proteins associated with… (More)
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2013
2013
KMT2D (lysine (K)-specific methyltransferase 2D), formerly named MLL2 (myeloid/lymphoid or mixed-lineage leukemia 2, also known… (More)
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Highly Cited
2013
Highly Cited
2013
Enhancers play a central role in cell-type-specific gene expression and are marked by H3K4me1/2. Active enhancers are further… (More)
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