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KLHL3 gene

Known as: KLHL3, KIAA1129, KELCH-LIKE 3 
 
National Institutes of Health

Papers overview

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2017
2017
Interaction between the acidic motif (AM) of protein kinase WNK4 and the Kelch domain of KLHL3 are involved in the pathogenesis… Expand
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2017
2017
WNK-OSR1/SPAK-NCC signaling cascade is important for regulating salt balance and blood pressure. Activation of WNK-OSR1/SPAK-NaCl… Expand
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2016
2016
Pseudohypoaldosteronism type II (PHA II) is a renal tubular disease that causes hyperkalemia, hypertension, and metabolic… Expand
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2016
2016
OBJECTIVE Familial Hyperkalemic Hypertension (FHHt) is caused by mutations in WNK1, WNK4, KLHL3 or CUL3 (cullin-3). Patients with… Expand
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2015
2015
We reported that kelch-like protein 3 (KLHL3)-Cullin3 E3 ligase ubiquitinates with-no-lysine kinase 4 (WNK4) and that impaired… Expand
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2014
2014
The study of families with rare inherited forms of hypo- and hyper-tension has been one of the most successful strategies to… Expand
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Highly Cited
2013
Highly Cited
2013
The WNK (with no lysine kinase)-SPAK (SPS1-related proline/alanine-rich kinase)/OSR1 (oxidative stress-responsive kinase 1… Expand
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2013
2013
Mutations in the WNK1 and WNK4 genes result in an inherited hypertensive disease, pseudohypoaldosteronism type II (PHAII… Expand
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2013
2013
PKC (protein kinase C) θ is predominantly expressed in T-cells and is critically involved in immunity. Design of PKCθ-selective… Expand
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2000
2000
The Drosophila kelch protein is a structural component of ring canals and is required for oocyte maturation. Here, we report the… Expand
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