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Autophagy, a cellular self-eating mechanism, is important for maintaining cell survival and tissue homeostasis in various… Expand Cullin-RING ubiquitin ligases are the largest E3 ligase family in eukaryotes and are multiprotein complexes. In these complexes… Expand Cullin-RING ubiquitin ligases are the largest Ubiquitin ligase family in eukaryotes and are multi-protein complexes. In these… Expand Cullin 3 (Cul3)-family ubiquitin ligases use the BTB-domain-containing proteins for the recruitment of substrates, but the… Expand Ubiquitin chains are formed as structurally distinct polymers via different linkages, and several chain types including K33… Expand Respiratory distress syndrome (RDS) caused by preterm delivery is a major clinical problem with limited mechanistic insight. Late… Expand PURPOSE
The BTB-kelch protein KLEIP/KLHL20 is an actin binding protein that regulates cell-cell contact formation and cell… Expand Tumor hypoxia is associated with disease progression and treatment failure, but the hypoxia signaling mechanism is not fully… Expand Death‐associated protein kinase (DAPK) was identified as a mediator of interferon (IFN)‐induced cell death. How IFN controls DAPK… Expand Sprouting and invasive migration of endothelial cells are important steps of the angiogenic cascade. Vascular endothelial growth… Expand