KIAA1524 wt Allele

Known as: Autoantigen, 90-kD Gene, CIP2A, p90 
Human KIAA1524 wild-type allele is located in the vicinity of 3q13.13 and is approximately 44 kb in length. This allele, which encodes protein CIP2A… (More)
National Institutes of Health

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KIAA1524 gene
Stimulation of Cell Proliferation

Papers overview

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Highly Cited
2013
Highly Cited
2013
Senescence sensitivity of breast cancer cells is defined by positive feedback loop between CIP2A and E2F1.
UNLABELLED Senescence induction contributes to cancer therapy responses and is crucial for p53-mediated tumor suppression… (More)
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Review
2013
Review
2013
Cancerous inhibitor of protein phosphatase 2A, an emerging human oncoprotein and a potential cancer therapy target.
Protein phosphatase 2A (PP2A) complexes function as tumor suppressors by inhibiting the activity of several critical oncogenic… (More)
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Highly Cited
2011
Highly Cited
2011
PP2A impaired activity is a common event in acute myeloid leukemia and its activation by forskolin has a potent anti-leukemic effect
Protein phosphatase 2A (PP2A) is a human tumor suppressor that inhibits cellular transformation by regulating the activity of… (More)
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Highly Cited
2011
Highly Cited
2011
Cancerous inhibitor of PP2A (CIP2A) at diagnosis of chronic myeloid leukemia is a critical determinant of disease progression.
Prospective identification of patients whose chronic myeloid leukemia (CML) will progress to blast crisis is currently not… (More)
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2011
2011
Increase in CIP2A expression is associated with doxorubicin resistance.
The cancerous inhibitor of protein phosphatase 2A (CIP2A) increases the migration and metastasis of various cancer cells… (More)
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Highly Cited
2010
Highly Cited
2010
CIP2A mediates effects of bortezomib on phospho-Akt and apoptosis in hepatocellular carcinoma cells
Previously, we reported that Akt inactivation determines the sensitivity of hepatocellular carcinoma (HCC) cells to bortezomib… (More)
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Highly Cited
2010
Highly Cited
2010
CIP2A is Overexpressed in Non-Small Cell Lung Cancer and Correlates with Poor Prognosis
Cancerous inhibitor of protein phosphatase 2A (CIP2A) is an oncoprotein inhibiting proteolytic degradation of c-MYC. In this… (More)
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Highly Cited
2009
Highly Cited
2009
CIP2A is associated with human breast cancer aggressivity.
PURPOSE To investigate the clinical relevance of the recently characterized human oncoprotein cancerous inhibitor of protein… (More)
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Highly Cited
2009
Highly Cited
2009
MYC-dependent regulation and prognostic role of CIP2A in gastric cancer.
BACKGROUND Cancerous inhibitor of protein phosphatase 2A (CIP2A) is a recently identified human oncoprotein that stabilizes the c… (More)
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Highly Cited
2007
Highly Cited
2007
CIP2A Inhibits PP2A in Human Malignancies
Inhibition of protein phosphatase 2A (PP2A) activity has been identified as a prerequisite for the transformation of human cells… (More)
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