KDM1A gene

Known as: lysine demethylase 1A, KDM1A, KIAA0601 
This gene is involved in the regulation of both transcription and histone methylation.

Topic mentions per year

Topic mentions per year

1997-2017
05010019972017

Papers overview

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Highly Cited
2012
Highly Cited
2012
Using a mouse model of human MLL-AF9 leukemia, we identified the lysine-specific demethylase KDM1A (LSD1 or AOF2) as an essential… (More)
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Highly Cited
2012
Highly Cited
2012
Acute promyelocytic leukemia (APL), a cytogenetically distinct subtype of acute myeloid leukemia (AML), characterized by the t(15… (More)
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Highly Cited
2009
Highly Cited
2009
Histone methylation and DNA methylation cooperatively regulate chromatin structure and gene activity. How these two systems… (More)
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Highly Cited
2009
Highly Cited
2009
Lysine-specific demethylase 1 (LSD1) exerts pathway-specific activity in animal development and has been linked to several high… (More)
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Highly Cited
2008
Highly Cited
2008
Although the role of liganded nuclear receptors in mediating coactivator/corepressor exchange is well-established, little is… (More)
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Highly Cited
2007
Highly Cited
2007
p53, the tumour suppressor and transcriptional activator, is regulated by numerous post-translational modifications, including… (More)
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Highly Cited
2007
Highly Cited
2007
Precise control of transcriptional programmes underlying metazoan development is modulated by enzymatically active co-regulatory… (More)
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Highly Cited
2007
Highly Cited
2007
Posttranslational modifications of histones, such as methylation, regulate chromatin structure and gene expression. Recently… (More)
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Highly Cited
2005
Highly Cited
2005
Gene regulation in eukaryotes requires the coordinate interaction of chromatin-modulating proteins with specific transcription… (More)
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Highly Cited
2005
Highly Cited
2005
LSD1 is a recently identified human lysine (K)-specific histone demethylase. LSD1 is associated with HDAC1/2; CoREST, a SANT… (More)
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