FAQ

KAL1 wt Allele

Known as: KALIG-1, KMS, HHA 
Human KAL1 wild-type allele is located in the vicinity of Xp22.32 and is approximately 203 kb in length. This allele, which encodes anosmin-1 protein… (More)

Topic mentions per year

Topic mentions per year

1983-2017
051019832017

Related topics

Related topics

11 relations
ANOS1 geneCell AdhesionCell MovementHomo sapiens
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Related mentions per year

Related mentions per year

1936-2018
19401960198020002020
KAL1 wt Allele
Wound Healing
cell growth
Cell Adhesion
Morphogenesis
Homo sapiens

Papers overview

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Highly Cited
2006
Highly Cited
2006
Array CGH identifies distinct DNA copy number profiles of oncogenes and tumor suppressor genes in chromosomal- and microsatellite-unstable sporadic colorectal carcinomas
DNA copy number changes represent molecular fingerprints of solid tumors and are as such relevant for better understanding of… (More)
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2004
2004
The product of X-linked Kallmann's syndrome gene (KAL1) affects the migratory activity of gonadotropin-releasing hormone (GnRH)-producing neurons.
X-linked Kallmann's syndrome (KS) is a genetic disease characterized by anosmia and hypogonadism due to impairment in the… (More)
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2002
2002
The role of prior pubertal development, biochemical markers of testicular maturation, and genetics in elucidating the phenotypic heterogeneity of idiopathic hypogonadotropic hypogonadism.
As our knowledge of the molecular mechanisms underlying idiopathic hypogonadotropic hypogonadism (IHH) expands, it becomes… (More)
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2001
2001
The importance of autosomal genes in Kallmann syndrome: genotype-phenotype correlations and neuroendocrine characteristics.
Kallmann syndrome (KS) consists of congenital, isolated, idiopathic hypogonadotropic hypogonadism (IHH) and anosmia. The gene… (More)
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2001
2001
Idiopathic gonadotrophin deficiency: genetic questions addressed through phenotypic characterization.
OBJECTIVE The association of idiopathic hypogonadotrophic hypogonadism (IHH) with congenital olfactory deficit defines Kallmann's… (More)
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Highly Cited
2000
Highly Cited
2000
Evolution of human and non-human primate CC chemokine receptor 5 gene and mRNA. Potential roles for haplotype and mRNA diversity, differential haplotype-specific transcriptional activity, and altered…
Polymorphisms in CC chemokine receptor 5 (CCR5), the major coreceptor of human immunodeficiency virus 1 (HIV-1) and simian… (More)
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1996
1996
Initial characterization of anosmin-1, a putative extracellular matrix protein synthesized by definite neuronal cell populations in the central nervous system.
The KAL gene is responsible for the X-chromosome linked form of Kallmann's syndrome in humans. Upon transfection of CHO cells… (More)
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1993
1993
Heterogeneity in the mutations responsible for X chromosome-linked Kallmann syndrome.
Kallmann syndrome represents the association of hypogonadotropic hypogonadism with anosmia. Three modes of transmission, X… (More)
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1992
1992
Structure of the X–linked Kallmann syndrome gene and its homologous pseudogene on the Y chromosome
The gene for the X-linked Kallmann syndrome (KAL), a developmental disorder characterized by hypogonadotropic hypogonadism and… (More)
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Highly Cited
1991
Highly Cited
1991
The candidate gene for the X-linked Kallmann syndrome encodes a protein related to adhesion molecules.
Kallmann syndrome associates hypogonadotropic hypogonadism and anosmia and is probably due to a defect in the embryonic migration… (More)
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