Juvenile hemochromatosis

Known as: Hemochromatosis, type 2, hemochromatosis juvenile, HFE2 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

1981-2017
051019812017

Papers overview

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Highly Cited
2008
Highly Cited
2008
We developed and validated the first serum enzyme-linked immunosorbent assay for hepcidin, the principal iron-regulatory hormone… (More)
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Highly Cited
2006
Highly Cited
2006
Hepcidin is a key regulator of systemic iron homeostasis. Hepcidin deficiency induces iron overload, whereas hepcidin excess… (More)
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Highly Cited
2005
Highly Cited
2005
Hereditary hemochromatosis is an iron-overload disorder resulting from mutations in proteins presumed to be involved in the… (More)
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Highly Cited
2005
Highly Cited
2005
Hepcidin is the principal regulator of iron absorption in humans. The peptide inhibits cellular iron efflux by binding to the… (More)
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Highly Cited
2005
Highly Cited
2005
Mutations in a recently identified gene HJV (also called HFE2, or repulsive guidance molecule C, RgmC) are the major cause of… (More)
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Highly Cited
2005
Highly Cited
2005
Iron homeostasis plays a critical role in many physiological processes, notably synthesis of heme proteins. Dietary iron sensing… (More)
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Highly Cited
2004
Highly Cited
2004
Juvenile hemochromatosis is an early-onset autosomal recessive disorder of iron overload resulting in cardiomyopathy, diabetes… (More)
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2003
2003
OBJECTIVE To evaluate whether arthropathy is associated with juvenile hemochromatosis and, if so, to assess the relationship… (More)
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2001
2001
Hereditary hemochromatosis (HH) is a genetically heterogeneous disease. The HFE gene resides on chromosome 6 and its mutations… (More)
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Highly Cited
1999
Highly Cited
1999
Juvenile hemochromatosis (JH) is an autosomal recessive disorder that leads to severe iron loading in the 2d to 3d decade of life… (More)
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