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JNJ 42041935

Known as: JNJ-42041935, JNJ42041935 
National Institutes of Health

Papers overview

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2019
2019
Nonhypoxic pharmacological stabilization of Hypoxia Inducible Factor 1α: Effects on dopaminergic differentiation of human neural stem cells
Parkinson's disease is a neurodegenerative disease resulting in degeneration of midbrain dopaminergic neurons. Exploratory… 
2018
2018
Inhibition of prolyl hydroxylase domain proteins selectively enhances venous thrombus neovascularisation.
2018
2018
Title A role for prolyl hydroxylase domain proteins in hippocampalsynaptic plasticity
Hypoxia-inducible factors (HIFs) are key transcriptional regulators that play a major role in oxygen homeostasis. HIF activity is… 
2017
2017
Hypoxia-inducible factor 1 in clinical and experimental aortic aneurysm disease.
2016
2016
The stabilization of hypoxia inducible factor modulates differentiation status and inhibits the proliferation of mouse embryonic stem cells.
2013
2013
A role for prolyl hydroxylase domain proteins in hippocampal synaptic plasticity
Hypoxia‐inducible factors (HIFs) are key transcriptional regulators that play a major role in oxygen homeostasis. HIF activity is… 
Highly Cited
2011
Highly Cited
2011
Pharmacological Characterization of 1-(5-Chloro-6-(trifluoromethoxy)-1H-benzoimidazol-2-yl)-1H-pyrazole-4-carboxylic Acid (JNJ-42041935), a Potent and Selective Hypoxia-Inducible Factor Prolyl…
The hypoxia-inducible factor (HIF) prolyl hydroxylase (PHD) enzymes represent novel targets for the treatment of anemia… 
2010
2010
American Chemical Society-239th national meeting--Investigating new therapeutic candidates: part 2. 21-25 March 2010, San Francisco, CA, USA.
  • K. Kirkham
  • IDrugs : the investigational drugs journal
  • 2010
  • Corpus ID: 44822323
The American Chemical Society 239th National Meeting, held in San Francisco, included topics covering developments related to the… 
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