JAG2 gene

Known as: JAG2, Jagged 2 Gene, SERRATE 2 
This gene plays a role in cell fate determination.

Topic mentions per year

Topic mentions per year

1989-2016
051019892016

Papers overview

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2014
2014
Osteosarcoma (OS) is the most common primary malignancy of bone and is usually associated with poor prognosis due to its high… (More)
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2012
2012
The purpose of this study was to identify the pathways associated with the ability of CD138(+) human myeloma cells to form… (More)
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2011
2011
Several studies have revealed links between hypoxia and activation of Notch in solid tumors. While most reports have focused on… (More)
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2010
2010
Ectopic Myc expression plays a key role in human tumorigenesis, and Myc dose-dependent tumorigenesis has been well established in… (More)
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2009
2009
Multiple myeloma (MM) is a clonal B-cell neoplasm that accounts for 10% of all malignant hematologic neoplasms and that affects… (More)
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Highly Cited
2006
Highly Cited
2006
WNT, Notch, FGF, and Hedgehog signaling pathways network together during embryogenesis, tissue regeneration, and carcinogenesis… (More)
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Highly Cited
2005
Highly Cited
2005
The mammalian auditory sensory epithelium, the organ of Corti, contains sensory hair cells and nonsensory supporting cells… (More)
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Highly Cited
2004
Highly Cited
2004
The NOTCH ligand, JAG2, was found to be overexpressed in malignant plasma cells from multiple myeloma (MM) patients and cell… (More)
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Highly Cited
2002
Highly Cited
2002
The p53 tumor suppressor is a transcription factor that regulates cell growth and death in response to environmental stimuli such… (More)
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2000
2000
The genomic sequence of the human Jagged2 (JAG2) gene, which encodes a ligand for the Notch receptors, was determined. The 30-kb… (More)
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