Isotope-Coded Affinity Tag Protein Analysis

Known as: Isotope-Coded Affinity Tag Analysis, ICAT, ICAT Analysis 
Recognizing that only a single tryptic peptide is needed to quantify the expression of the corresponding parent protein, the ICAT reagent was… (More)
National Institutes of Health

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Highly Cited
2004
Highly Cited
2004
We describe here a multiplexed protein quantitation strategy that provides relative and absolute measurements of proteins in… (More)
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Highly Cited
2004
Highly Cited
2004
Classical proteomics combined two-dimensional gel electrophoresis (2-DE) for the separation and quantification of proteins in a… (More)
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2004
2004
An approach is described for identifying and quantifying oxidant-sensitive protein thiols using a cysteine-specific, acid… (More)
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Highly Cited
2004
Highly Cited
2004
An approach is described for the simultaneous identification and quantitation of oxidant-sensitive cysteine thiols in a complex… (More)
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Highly Cited
2003
Highly Cited
2003
Protein expression profiles in yeast cells, in response to salinity stress, were determined using the cleavable isotope-coded… (More)
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Highly Cited
2003
Highly Cited
2003
In order to identify and compare the protein content of very low quantity samples of high complexity, a protocol has been… (More)
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Highly Cited
2002
Highly Cited
2002
The effectiveness of proteome-wide protein identification and quantitative expression profiling is dependent on the ability of… (More)
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Highly Cited
2001
Highly Cited
2001
An approach to the systematic identification and quantification of the proteins contained in the microsomal fraction of cells is… (More)
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Highly Cited
2001
Highly Cited
2001
The combination of isotope coded affinity tag (ICAT) reagents and tandem mass spectrometry constitutes a new method for… (More)
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Highly Cited
1999
Highly Cited
1999
We describe an approach for the accurate quantification and concurrent sequence identification of the individual proteins within… (More)
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