Isothiocyanate

Known as: Isothiocyanates 
A chemical group containing the monovalent -N=C=S group. Isothiocyanate is the fundamental structure in many synthetic and biological active… (More)

Topic mentions per year

Topic mentions per year

1948-2017
010020019482016

Papers overview

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Highly Cited
2006
Highly Cited
2006
Reactive oxygen species (ROS) stimulate cell proliferation and induce genetic instability, and their increase in cancer cells is… (More)
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Highly Cited
2004
Highly Cited
2004
The bZIP transcription factor Nrf2 controls a genetic program that protects cells from oxidative damage and maintains cellular… (More)
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Highly Cited
2002
Highly Cited
2002
BACKGROUND Humans are exposed to substantial quantities of isothiocyanates and glucosinolates from vegetables. Since dietary… (More)
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Highly Cited
2001
Highly Cited
2001
The natural indoles 3,3'-diindolylmethane (DIM), ascorbigen (ASG), indole-3-carbinol (I3C), and indolo[3,2-b]carbazole (ICZ), as… (More)
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Highly Cited
2000
Highly Cited
2000
Sulforaphane is an isothiocyanate that is present naturally in widely consumed vegetables and has a particularly high… (More)
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Highly Cited
2000
Highly Cited
2000
Epidemiological studies have linked consumption of broccoli to a reduced risk of colon cancer in individuals with the glutathione… (More)
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Highly Cited
2000
Highly Cited
2000
BACKGROUND Dietary isothiocyanates inhibit lung carcinogenesis in laboratory animals but human data are limited. Glutathione S… (More)
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Highly Cited
1998
Highly Cited
1998
Isothiocyanates and their naturally occurring glucosinolate precursors are widely consumed as part of a diet rich in cruciferous… (More)
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Highly Cited
1998
Highly Cited
1998
Isothiocyanates exert strong anticarcinogenic effects in a number of animal models of cancer, presumably by modulation of… (More)
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Highly Cited
1997
Highly Cited
1997
Induction of phase 2 detoxication enzymes [e.g., glutathione transferases, epoxide hydrolase, NAD(P)H: quinone reductase, and… (More)
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