Isoacitretin
National Institutes of Health
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LC- ESI- MS/MS simultaneous bioanalytical method was developed to determine acitretin and its metabolite isoacitretin in human…
Certain retinoids have been shown in rats and mice to induce the hepatic cytochrome P-450 enzyme system, and evidence from our…
1. The metabolism of acitretin and its 13-cis isomer, isoacitretin, has been investigated in the in situ isolated perfused rat…
The ability of glutathione to catalyze the cis-trans isomerization of acitretin and isoacitretin was explored. Glutathione…
Etretinate accumulates in adipose tissue; this appears to account for its long terminal elimination phase in psoriatic patients…