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Iron Regulatory Protein 2

Known as: IRE-BP2, IRP-2 RNA-binding protein, IREB2 Protein 
A multifunctional iron-sulfur protein that is both an iron regulatory protein and cytoplasmic form of aconitate hydratase. It binds to iron… 
National Institutes of Health

Papers overview

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Highly Cited
2017
Highly Cited
2017
In this study, Chen and colleagues investigated the biological function of ferredoxin reductase (FDXR), a target of p53. They… 
Highly Cited
2009
Highly Cited
2009
Iron Sensor Intracellular iron is an essential cofactor for many proteins, but can also damage macromolecules, so its levels are… 
Highly Cited
2009
Highly Cited
2009
Osteoclasts are acid-secreting polykaryons that have high energy demands and contain abundant mitochondria. How mitochondrial… 
Highly Cited
2006
Highly Cited
2006
Iron homeostasis in the brain: complete iron regulatory protein 2 deficiency without symptomatic neurodegeneration in the mouse 
Highly Cited
2005
Highly Cited
2005
Iron regulatory protein 2 (IRP2)-deficient mice have been reported to suffer from late-onset neurodegeneration by an unknown… 
Highly Cited
2003
Highly Cited
2003
Iron regulatory protein 2 (IRP2) is a central regulator of cellular iron homeostasis due to its regulation of specific mRNAs… 
Highly Cited
1998
Highly Cited
1998
The ability of iron to catalyze formation of reactive oxygen species significantly contributes to its toxicity in cells and… 
Highly Cited
1995
Highly Cited
1995
Iron regulatory proteins (IRP1 and IRP2) are RNA-binding proteins that bind to specific structures, termed iron-responsive… 
Highly Cited
1995
Highly Cited
1995
Iron regulatory proteins (IRP1 and IRP2) are RNA-binding proteins that bind to stem-loop structures, termed iron-responsive… 
Highly Cited
1995
Highly Cited
1995
Iron regulatory proteins (IRPs) regulate the expression of genes involved in iron metabolism whose transcripts contain RNA stem…