Irido-corneal dysgenesis

Known as: Anterior chamber mesodermal anomalies, Anterior chamber cleavage disorder, Anterior segment mesencyhmal dysgenesis 
Abnormal development (dysgenesis) of the anterior segment of the eye globe. These structures are mainly of mesenchymal origin. [DDD:ncarter]
National Institutes of Health

Papers overview

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Review
2008
Review
2008
Glaucoma is a leading cause of blindness, estimated to affect 60 million people by 2010, and represents a heterogeneous group of… (More)
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Highly Cited
2007
Highly Cited
2007
PURPOSE To improve the understanding of Axenfeld-Rieger Malformation (ARM)-associated glaucoma and to determine the best glaucoma… (More)
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Highly Cited
2007
Highly Cited
2007
Ocular anterior segment dysgenesis (ASD) is a complex and poorly understood group of conditions. A large proportion of… (More)
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Highly Cited
2006
Highly Cited
2006
Axenfeld-Rieger ocular dysgenesis is associated with mutations of the human PITX2 and FOXC1 genes, which encode transcription… (More)
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2005
2005
Members of the type IV collagen family are essential components of all basement membranes (BMs) and define structural stability… (More)
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Highly Cited
2002
Highly Cited
2002
Human congenital cataract and ocular anterior segment dysgenesis both demonstrate extensive genetic and phenotypic heterogeneity… (More)
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Highly Cited
2001
Highly Cited
2001
Dysgenesis of the anterior segment of the eye delineates a spectrum of human developmental disorders that show wide phenotypic… (More)
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Highly Cited
2001
Highly Cited
2001
Glaucoma is a blinding disease usually associated with high intraocular pressure (IOP). In some families, abnormal anterior… (More)
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1999
1999
Mutations within the RIEG1 homeobox gene on chromosome 4q25 have previously been reported in association with Rieger syndrome. We… (More)
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Highly Cited
1993
Highly Cited
1993
To explore the physiological roles of transforming growth factor alpha (TGF alpha), we disrupted the mouse gene by homologous… (More)
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