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Investigational New Drugs

Known as: Investigational Drugs, drugs investigational, Drugs, Investigational New 
A substance that has been tested in a laboratory and has gotten approval from the U.S. Food and Drug Administration (FDA) to be tested in people. An… 
National Institutes of Health

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Clinical TrialsDrug ApprovalDrug EvaluationExperimental drug

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2015
Review
2015
Safety and Efficacy of a Combination of Venetoclax (GDC-0199/ABT-199) and Obinutuzumab in Patients with Relapsed/Refractory or Previously Untreated Chronic Lymphocytic Leukemia - Results from a Phase…
![Graphic][1] Introduction Treatment of patients (pts) with relapsed/refractory (R/R) chronic lymphocytic leukemia (CLL) with… 
Review
2012
Review
2012
Current investigational drugs in psoriasis
Introduction : The advent of biologic therapies has revolutionized the treatment of psoriasis. Increased understanding of… 
Review
2012
Review
2012
Can next-generation antibodies offset biosimilar competition?
With the first biosimilar version of a monoclonal antibody now under regulatory review in the European Union, which R&D… 
Highly Cited
2011
Highly Cited
2011
Lessons from the trenches--a high-functioning primary care clinic.
Clinica Family Health Services, a Denver-area community health center serving a low-income population, is on the front lines of a… 
2009
2009
Expanded access to investigational drugs for treatment use. Final rule.
The Food and Drug Administration (FDA) is amending its regulations on access to investigational new drugs for the treatment of… 
2009
2009
Translational development of mesenchymal stem cell therapy for cardiovascular diseases.
Currently, a growing number of small clinical trials are testing the impact of cell-based therapies for heart disease.1 In order… 
2002
2002
The new sulindac derivative IND 12 reverses Ras-induced cell transformation.
The nonsteroidal anti-inflammatory drug Sulindac has chemopreventive and antitumorigenic properties. Its metabolites induce… 
1995
1995
Cyclo‐oxygenase mediation of endotoxin‐induced fever, anterior and posterior pituitary hormone release, and hypothalamic c‐Fos expression in the prepubertal pig
Prepubertal pigs (n = 8) treated with bacterial endotoxin (20 micrograms lipopolysaccharide; LPS) exhibited a sustained (4 h… 
1988
1988
Psychological reactions of individuals at risk for AIDS during an experimental drug trial.
1976
1976
Cerebral microvascular injury in experimental drug abuse.
An experimental drug abuse research project is reported, in which monkeys and rats were placed on various I.V. amphetamine… 
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