Intervertebral Disc Degeneration

Known as: Degeneration, Disc, Disk Degradation, Degenerations, Disc 
Degenerative changes in the INTERVERTEBRAL DISC due to aging or structural damage, especially to the vertebral end-plates.
National Institutes of Health

Papers overview

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Review
2007
Review
2007
Degeneration of the intervertebral disc has been implicated in chronic low back pain. Type II collagen and proteoglycan… (More)
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Highly Cited
2007
Highly Cited
2007
Current evidence implicates intervertebral disc degeneration as a major cause of low back pain, although its pathogenesis is… (More)
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Highly Cited
2007
Highly Cited
2007
STUDY DESIGN A reliability study was conducted. OBJECTIVE.: To modify a grading system for lumbar disc degeneration and to test… (More)
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Highly Cited
2006
Highly Cited
2006
STUDY DESIGN We collected the specimens of lumbar intervertebral disc (i.e., the symptomatic degenerative disc) from patients… (More)
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Highly Cited
2001
Highly Cited
2001
Autogenous implantation of nucleus pulposus or nucleus pulposus cells that were activated by coculture retards intervertebral… (More)
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Highly Cited
2000
Highly Cited
2000
STUDY DESIGN Mechanical testing of cadaveric lumbar motion segments. OBJECTIVES To test the hypothesis that minor damage to a… (More)
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Highly Cited
2000
Highly Cited
2000
STUDY DESIGN Cross-sectional magnetic resonance imaging (MRI) study. OBJECTIVES To study the relation of low back pain (LBP) to… (More)
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Highly Cited
1998
Highly Cited
1998
STUDY DESIGN A study in genetic epidemiology of disc degeneration, based on lifetime exposure data, findings on magnetic… (More)
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Review
1995
Review
1995
Human intervertebral discs undergo age-related degenerative changes that contribute to some of the most common causes of… (More)
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Highly Cited
1981
Highly Cited
1981
The distribution of the principal matrix components, collagen, proteoglycans and water, across the diameter of human normal and… (More)
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