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Internal Ribosome Entry Sites

Known as: IRES, Internal Ribosome Entry Site, Internal Ribosome Entry Sites [Chemical/Ingredient] 
Internal ribosome entry site (IRES) is a translational cis-acting element that directs ribosomes to the start codon by a cap-independent mechanism… 
National Institutes of Health

Related topics

Related topics

3 relations
Chromosomesaspects of radiation effectsphysiological aspects

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2008
2008
Attenuation of Rabies Virus Replication and Virulence by Picornavirus Internal Ribosome Entry Site Elements
ABSTRACT Gene expression of nonsegmented negative-strand RNA viruses is regulated at the transcriptional level and relies on the… 
2008
2008
A Dormant Internal Ribosome Entry Site Controls Translation of Feline Immunodeficiency Virus
ABSTRACT The characterization of internal ribosome entry sites (IRESs) in virtually all lentiviruses prompted us to investigate… 
2004
2004
Comparative analysis of intracellular trans-splicing ribozyme activity against hepatitis C virus internal ribosome entry site.
Internal ribosome entry site (IRES) of the hepatitis C virus (HCV) is known to be essential for HCV replication and most… 
2001
2001
The internal ribosome entry site (IRES) of hepatitis C virus visualized by electron microscopy.
Translation of hepatitis C virus (HCV) RNA is initiated via the internal ribosome entry site (IRES), located within the 5… 
2001
2001
The Ribosome Binding Site of Hepatitis C Virus mRNA
ABSTRACT Hepatitis C virus (HCV) infects an estimated 170 million people worldwide, the majority of whom develop a chronic… 
Highly Cited
2000
Highly Cited
2000
Cell Type-Specific Enhancement of Hepatitis C Virus Internal Ribosome Entry Site-Directed Translation due to 5′ Nontranslated Region Substitutions Selected during Passage of Virus in Lymphoblastoid…
ABSTRACT Low-level replication of hepatitis C virus (HCV) in cultured lymphoblastoid cells inoculated with H77 serum inoculum led… 
Review
1999
Review
1999
Internal ribosome entry sites (IRESs): reality and use
IRESs are known to recruit ribosomes directly, without a previous scanning of untranslated region of mRNA by the ribosomes. IRESs… 
Highly Cited
1997
Highly Cited
1997
The sequence element of the internal ribosome entry site and a 25-kilodalton cellular protein contribute to efficient internal initiation of translation of hepatitis C virus RNA
Translation of hepatitis C virus (HCV) RNA is initiated by internal entry of ribosomes into the 5' noncoding region (NCR). This… 
Review
1995
Review
1995
Structure and function of the hepatitis C virus internal ribosome entry site.
Human hepatitis C virus (HCV) infects hepatocytes and the viral infection often develops into chronic disease, liver cirrhosis… 
1994
1994
trans complementation by RNA of defective foot-and-mouth disease virus internal ribosome entry site elements
A region of about 435 bases from the 5' noncoding region of foot-and-mouth disease virus RNA directs internal initiation of… 
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