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Interleukin-16, human

Known as: Interleukin-16, IL16, Lymphocyte Chemoattractant Factor 
Interleukin-16 (121 aa, ~12 kDa) is encoded by the human IL16 gene. This protein plays a role in leukocyte chemotaxis.
National Institutes of Health

Related topics

Related topics

14 relations
Cell Proliferation Regulatory ProcessChemotaxisCytokine GeneCytokine Network Pathway

Broader (1)

Interleukin-16

Papers overview

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Highly Cited
2014
Highly Cited
2014
Extending single mode performance of all-solid large-mode-area single trench fiber.
We report a novel "single trench fiber" design for mode area scaling of the fundamental mode while offering effective single mode… 
Review
2014
Review
2014
Regulation of Cellular Processes by Interleukin‐16 in Homeostasis and Cancer
Interleukin‐16 (IL‐16) is generated as a precursor molecule that is cleaved by caspase‐3 to produce a pro‐IL‐16 molecule that… 
2013
2013
Depletion of tristetraprolin in breast cancer cells increases interleukin-16 expression and promotes tumor infiltration with monocytes/macrophages.
The RNA-binding protein tristetraprolin (TTP) destabilizes target messenger RNAs (mRNAs) containing AU-rich elements within their… 
Highly Cited
2013
Highly Cited
2013
Interleukin-16 Promotes Cardiac Fibrosis and Myocardial Stiffening in Heart Failure with Preserved Ejection Fraction
Background Chronic heart failure (CHF) with preserved left ventricular (LV) ejection fraction (HFpEF) is observed in half of all… 
Highly Cited
2009
Highly Cited
2009
Intake of meat, meat mutagens, and iron and the risk of breast cancer in the Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial
Background:Epidemiological evidence on meat intake and breast cancer is inconsistent, with little research on potentially… 
2003
2003
The -295T-to-C promoter polymorphism of the IL-16 gene is associated with Crohn's disease.
Highly Cited
2002
Highly Cited
2002
Expression of Transcription Factor AML-2 (RUNX3, CBFα-3) Is Induced by Epstein-Barr Virus EBNA-2 and Correlates with the B-Cell Activation Phenotype
ABSTRACT To identify cell proteins regulated by the Epstein-Barr virus (EBV) transcription factor EBNA-2, we analyzed a cell line… 
2000
2000
A new polymorphism in the promoter region of the human interleukin-16 (IL-16) gene
Interleukin 16 (IL-16) is a chemotactic cytokine which binds to CD4 and affects T cell activation. Here we report a novel single… 
Highly Cited
1998
Highly Cited
1998
Circulating interleukin-16 in systemic lupus erythematosus.
OBJECTIVE To investigate the relationship between interleukin (IL)-16 and systemic lupus erythematosus (SLE). METHODS Serum… 
Review
1998
Review
1998
Signaling and functional properties of interleukin-16.
Interleukin-16 is secreted from a variety of immune cells as a peptide of 17 kDa which aggregates into tetrameric form essential… 
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