Interleukin-12 Subunit p35

Known as: IL12A Protein, Interleukin-12 Subunit Alpha, NKSF1 
Interleukin-12 subunit alpha (219 aa, ~25 kDa) is encoded by the human IL12A gene. This protein plays a role in cytokine signaling in both T-cells… (More)
National Institutes of Health

Papers overview

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Highly Cited
2009
Highly Cited
2009
Allergic airway inflammation is characterized by marked in situ changes in gene and protein expression, yet the role of microRNAs… (More)
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Highly Cited
2008
Highly Cited
2008
Our genome-wide association study of celiac disease previously identified risk variants in the IL2–IL21 region. To identify… (More)
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Highly Cited
2008
Highly Cited
2008
We analyzed interleukin (IL) 12 and IL-23 production by monocyte-derived dendritic cells (mono-DCs). Mycobacterium tuberculosis… (More)
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Highly Cited
2005
Highly Cited
2005
Dendritic cells (DC) produce interleukin-12 (IL-12) in response to Toll-like receptor (TLR) activation. Two major TLR signaling… (More)
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Highly Cited
2005
Highly Cited
2005
BACKGROUND It has been suggested that Crohn's disease (CD) is associated with an exaggerated T-helper 1 cytokine response… (More)
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Highly Cited
2004
Highly Cited
2004
Identifying regions of the human genome that have been targets of natural selection will provide important insights into human… (More)
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Highly Cited
2002
Highly Cited
2002
IL-23 is a heterodimeric cytokine composed of the IL-12p40 "soluble receptor" subunit and a novel cytokine-like subunit related… (More)
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Highly Cited
2002
Highly Cited
2002
Interleukin-12 (IL12) is a cytokine that is secreted by activated phagocytes and dendritic cells and that induces interferon… (More)
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Highly Cited
2001
Highly Cited
2001
Interleukin-12 p70 (IL-12p70) heterodimer, composed of p35 and p40 subunits, is a major Th1-driving cytokine, promoting cell… (More)
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Highly Cited
1998
Highly Cited
1998
To analyze the roles of interleukin-12 (IL-12) and the IL-12-dependent Th1 response in resistance to Cryptococcus neoformans, we… (More)
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