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Interleukin 12 Receptor Beta

Known as: Interleukin 12 Receptor, Interleukin-12 Receptor, High Affinity Interleukin 12 Receptor 
Human high affinity Interleukin 12 Receptor is composed of Interleukin 12 Receptor Beta 1 Chain (I12RB1) and Interleukin 12 Receptor Beta 2 Chain… 
National Institutes of Health

Papers overview

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Highly Cited
2013
Highly Cited
2013
PURPOSE Mounting evidence suggests that tumor-infiltrating immune cells have prognostic value for patients with solid organ… 
Highly Cited
2011
Highly Cited
2011
BACKGROUND Chronic mucocutaneous candidiasis (CMC) is characterized by susceptibility to candida infection of skin, nails, and… 
Highly Cited
2003
Highly Cited
2003
We describe 3 siblings with interleukin-12 receptor beta1 (IL-12Rbeta1) deficiency, a known genetic etiology of clinical disease… 
Highly Cited
2002
Highly Cited
2002
Host genetic factors may be important determinants of susceptibility to tuberculosis, and several candidate gene polymorphisms… 
Highly Cited
2002
Highly Cited
2002
Clinical and experimental observations suggest that minimal-change nephrotic syndrome (MCNS) results from T cell dysfunction, via… 
Highly Cited
2001
Highly Cited
2001
Interleukin-12 (IL-12) plays an important role in the production of interferon gamma (IFN-gamma) and is essential for protection… 
Highly Cited
2000
Highly Cited
2000
Interleukin (IL)-12 plays a critical role in modulating the activities of natural killer (NK) cells and T lymphocytes. In animal… 
Highly Cited
1998
Highly Cited
1998
In humans, interferon gamma (IFN-gamma) receptor deficiency leads to a predisposition to mycobacterial infections and impairs the… 
Highly Cited
1998
Highly Cited
1998
Interleukin-12 (IL-12) is a cytokine that promotes cell-mediated immunity to intracellular pathogens by inducing type 1 helper T… 
Highly Cited
1997
Highly Cited
1997
The interleukin‐12 receptor (IL‐12R)β1 chain is an essential component of the functional IL‐12R on both human T and natural…