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Interleukin 12 Receptor Beta

Known as: Interleukin 12 Receptor, Interleukin-12 Receptor, High Affinity Interleukin 12 Receptor 
Human high affinity Interleukin 12 Receptor is composed of Interleukin 12 Receptor Beta 1 Chain (I12RB1) and Interleukin 12 Receptor Beta 2 Chain… Expand
National Institutes of Health

Papers overview

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Highly Cited
2013
Highly Cited
2013
PURPOSE Mounting evidence suggests that tumor-infiltrating immune cells have prognostic value for patients with solid organ… Expand
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Highly Cited
2011
Highly Cited
2011
BACKGROUND Chronic mucocutaneous candidiasis (CMC) is characterized by susceptibility to candida infection of skin, nails, and… Expand
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Highly Cited
2003
Highly Cited
2003
We describe 3 siblings with interleukin-12 receptor beta1 (IL-12Rbeta1) deficiency, a known genetic etiology of clinical disease… Expand
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Highly Cited
2002
Highly Cited
2002
Host genetic factors may be important determinants of susceptibility to tuberculosis, and several candidate gene polymorphisms… Expand
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Highly Cited
2002
Highly Cited
2002
Clinical and experimental observations suggest that minimal-change nephrotic syndrome (MCNS) results from T cell dysfunction, via… Expand
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Highly Cited
2001
Highly Cited
2001
Interleukin-12 (IL-12) plays an important role in the production of interferon gamma (IFN-gamma) and is essential for protection… Expand
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Highly Cited
2000
Highly Cited
2000
Interleukin (IL)-12 plays a critical role in modulating the activities of natural killer (NK) cells and T lymphocytes. In animal… Expand
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Highly Cited
1998
Highly Cited
1998
In humans, interferon gamma (IFN-gamma) receptor deficiency leads to a predisposition to mycobacterial infections and impairs the… Expand
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Highly Cited
1998
Highly Cited
1998
Interleukin-12 (IL-12) is a cytokine that promotes cell-mediated immunity to intracellular pathogens by inducing type 1 helper T… Expand
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1997
1997
The interleukin-12 receptor (IL-12R)beta1 chain is an essential component of the functional IL-12R on both human T and natural… Expand
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