Interferon Alfa-2a

Known as: Recombinant human interferon-alfa-2a, Alpha 2 Interferon, Interferon alpha-2a 
A non-glycosylated recombinant human alpha interferon, subtype 2a, produced in the bacterium E. coli. Interferon alpha-2a binds to its specific cell… (More)
National Institutes of Health

Papers overview

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Highly Cited
2009
Highly Cited
2009
PURPOSE A randomized, phase III trial demonstrated superiority of sunitinib over interferon alfa (IFN-alpha) in progression-free… (More)
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Highly Cited
2009
Highly Cited
2009
BACKGROUND Treatment guidelines recommend the use of peginterferon alfa-2b or peginterferon alfa-2a in combination with ribavirin… (More)
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Highly Cited
2008
Highly Cited
2008
Interferon-alpha (IFN-alpha) is a nonleukemogenic treatment of polycythemia vera (PV) able to induce cytogenetic remissions. Its… (More)
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Highly Cited
2008
Highly Cited
2008
PURPOSE Bevacizumab is an antibody that binds to vascular endothelial growth factor (VEGF) and has activity in metastatic renal… (More)
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Highly Cited
2007
Highly Cited
2007
BACKGROUND Since sunitinib malate has shown activity in two uncontrolled studies in patients with metastatic renal-cell carcinoma… (More)
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Highly Cited
2004
Highly Cited
2004
BACKGROUND Chronic hepatitis C virus (HCV) infection is a cause of major complications in persons who are also infected with the… (More)
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Highly Cited
2004
Highly Cited
2004
BACKGROUND Hepatitis C virus (HCV) infection is highly prevalent and is associated with substantial morbidity and mortality among… (More)
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Highly Cited
2003
Highly Cited
2003
BACKGROUND Imatinib, a selective inhibitor of the BCR-ABL tyrosine kinase, produces high response rates in patients with chronic… (More)
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Highly Cited
2002
Highly Cited
2002
BACKGROUND Treatment with peginterferon alfa-2a alone produces significantly higher sustained virologic responses than treatment… (More)
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Highly Cited
2000
Highly Cited
2000
BACKGROUND Covalent attachment of a 40-kd branched-chain polyethylene glycol moiety to interferon alfa-2a results in a compound… (More)
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